|United States Of America||Issued Patent||9,389,230||07/12/2016||2012-622|
|United States Of America||Published Application||20190195873||06/27/2019||2012-622|
Citrus greening disease, also known as huanglongbing (HLB), is a stubborn bacterial disease caused by insect-transmission and phloem-limited bacterial pathogens. It has been a serious threat to the US citrus industry, decimating many citrus trees and costing the economy $11B in damages annually. The most commonly used method of nucleic-acid based pathogen detection has issues with low-titer (low concentration of antibodies to antigen) and cannot handle the erratic distribution of the pathogens.
UCR researchers have developed a proof-of-concept for using secreted proteins of bacterial pathogens to detect bacterial diseases. These abundant and stable secreted proteins serve as robust detection markers for immunoassay-based diagnostics. Compared to current methods, this novel method is more high-throughput, economical, and able to monitor the pathogens dispersed throughout the plant transportation system.
citrus, citrus pathogens, citrus stubborn disease, CSD, HLB, S. Citri, fresh fruit, global foods, antibody-based serological detection, immunoassay-based diagnostic, plant bacterial disease, plant bacterial pathogen, huanglongbing, HLB, citrus greening disease, infected trees, tree disease, insect-transmitted disease, phloem