NH3 Polypeptide Driven Disease Resistance in Plants

Tech ID: 21021 / UC Case 2010-786-0


Researchers at the University of California, Davis have developed a method to enhance disease resistance in plants.

Full Description

Plants survive pathogen attack by using various defense strategies including the induction of pathogenesis-related (PR) genes. After an initial local infection, systemic acquired resistance (SAR) occurs which induces a set of PR genes, leading to enhanced resistance against a broad spectrum of pathogens. Constitutively active defense responses, however, waste energy and resources and lead to undesirable consequences such as dwarf plants.

Researchers at the University of California, Davis have developed a method that enhances disease resistance in plants by overexpression of NH3 polypeptide. Treatment in transgenic rice plants displayed enhanced induction of pathogen resistance genes without constitutively activating defense responses. Bacterial growth was reduced 10-fold in the transgenic plants and they exhibited higher sensitivity to benzothiadiazole and INA chemical treatment. This invention will make the use of chemical inducers more effective and reduce the amount of chemicals needed to achieve desired yields.


  • Enhanced plant resistance to a broad spectrum of pathogens (oomyces, bacteria and viruses)


  • Enhanced disease resistance
  • Does not constitutively activate plant defense responses
  • Reduction in the amount of chemicals needed

Related Materials

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 9,644,214 05/09/2017 2010-786


Learn About UC TechAlerts - Save Searches and receive new technology matches

Other Information


disease resistance, NH3, polypeptide, transgenic plants, systemic acquired resistance, SAR, constitutively active defense response

Categorized As