Researchers at UC San Diego have developed a smaller and higher resolution, single-particle, mass spectrometer based on a previously patented technique and instrument (ATOFMS). [See U.S. patents 5,681,752 and 5,998,215.]
The new instrument is fully automated, compact, faster, has a higher m/z range, higher sensitivity, and low power consumption. It analyzes data in real-time and uses a special robust software library, created with millions of particles, to apportion particles to specific sources "on-the-fly." The library, developed over a ten-year period, is extensive but is readily adaptable to new signatures.
The novel folded-Z design is much smaller than the existing transportable ATOFMS and detects 100 percent of ions up to m/z 2000. The instrument is operational and has undergone field testing.
Numerous potential applications exist, such as drug analysis, biowarfare detection of individual biological particles, cleanroom monitoring, on-line biological analysis (MALDI), environmental measurements of pollutants and toxic substances, atmospheric chemistry, and forensics.
This technology is available for licensing.
|United States Of America||Issued Patent||8,648,294||02/11/2014||2006-104|
|United States Of America||Issued Patent||8,626,449||01/07/2013||2006-104|