The invention allows for the determination of amino acid sequence tags from tandem mass spectrometry spectral pairs and subsequent peptide and modification identification through a database search utilizing extremely fast pattern matching.
This invention would present an improved method over tools, such as SEQUEST and MASCOT, by never comparing a spectrum against a database and simultaneously allowing for higher sensitivity in the detection of post-translational modifications.
The invention is useful to anyone interested in identifying peptides, proteins and post-translational modifications on Tandem Mass Spectrometry data from biological samples
protein identification, peptides, mass spectrometry, proteomics, post-translational modifications