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Active Nanoplatform with High Drug Loading Capacity for the Diagnosis and Treatment of Cancer

Researchers at the University of California, Davis have developed an active nanoplatform (F/HAPIN) for cancer diagnosis and therapy.

Single Fiber-Based Multimodal Biophotonic Imaging and Spectroscopy Platform

Researchers at the University of California, Davis have developed a highly flexible and reconfigurable optical imaging and spectroscopy platform.

Combined Individual Nanomaterial Enhancements for Total X-Ray Enhancement

Researchers at the University of California, Davis have developed a method to combine individual nanomaterial enhancements to achieve greater X-ray enhancement.

Transabdominal Fetal Blood Oximetry

Researchers at the University of California, Davis have developed a method and apparatus for clinical-grade transabdominal fetal blood oximetry.

Stationary X-Ray Source

Researchers at the University of California, Davis have developed an integrated method of providing a long lived, high output stationary X-ray source.

PVA Nanocarrier System for Controlled Drug Delivery

Researchers at the University of California, Davis have designed and synthesized a unique type of water-soluble, biodegradable targeting poly(vinyl alcohol) (PVA) nanocarrier system for controlled delivery of boronic acid containing drugs, chemotherapy agents, proteins, photodynamic therapy agents and imaging agents.

Novel Contrast Enhancement for Detection of Amyloid Beta Peptides using MRI, EPR, PET, and ESRM

Researchers at the University of California, Davis have developed nitroxide-coupled amyloid agents to produce contrast enhancement for amyloid beta peptide (Abeta) detection using MRI, EPR, PET, and ESRM.

Synthesis Technique to Achieve High-Anisotropy FeNi

Researchers at the University of California, Davis have developed an innovative synthesis approach to achieve high anisotropy L1 FeNi by combining physical vapor deposition and a high speed rapid thermal annealing (RTA).

Novel One-Step Preparation and Consolidation of the Iron Arsenide Based Superconductor Providing High Quality Ceramic Shapes

Researchers at the University of California, Davis have developed a one-step and spark plasma sintering consolidation method utilizing hydrides of potassium, sodium, lithium, and barium to prepare sintered and dense pellets of doped BaFe2As2 superconductors.

Novel Cyanobacteriochromes Responsive to Light in the Far-Red to Near-Infrared Region

Researchers at the University of California, Davis have identified new cyanobacteriochromes (CBCRs) that detect and fluoresce in the far-red and near-infrared region of the electromagnetic spectrum.

Dynamic Contrast Optical Coherence Tomography (DyC-OCT): An Improved Method to Quantify Blood Flow Dynamics in Deep Tissue and Microvasculature

Dynamic Contrast Optical Coherence Tomography (DyC-OCT) is a non-invasive technique that obtains high resolution images of blood flow dynamics in deep tissue. It involves real time imaging of the passage of a contrast agent through the vascular and capillary networks. Data analysis can then reveal detailed information on the temporal and spatial dynamics of blood flow.

Real-Time Fluorescence Lifetime Tracking

Researchers at the University of California, Davis have developed a novel technique for continuous acquisition, processing, and display of fluorescence lifetimes. This technique allows for rapid and non-invasive real-time tissue diagnosis through a single hand-held or biopsy fiber-optic probe.

Real-Time Tissue Assessment During Surgical Procedures

Researchers at the University of California, Davis have developed a novel method and device that allows removed tissue to be examined during the surgery to ensure that the excised tissue has 'clean margins'.

Novel Treatments for Neuroimmune-based Psychiatric Disorders

Researchers at the University of California, Davis have identified new targets that will serve as the foundation for developing new treatments along with companion biomarkers, for several neuroimmune-based psychiatric disorders. These targets are the result of unprecedented work employing both mouse and nonhuman primate disease models that has identified a shared set of immune molecules altered in the brains of these two very different species.

Imaging Guided Ablative Laser Surgery

Researchers at the University of California, Davis have devised an objective real-time method of visualizing the treatment area that will that will allow a laser surgeon to select appropriate ablative laser settings to treat a skin lesions and lesional tissues from other organ systems including, but not limited to: oral mucosa/gingiva, ear/nose and throat, esophagus, gastrointestinal, genitourinary, ophthalmologic and cardiopulmonary.

Diabodies for Use as Molecular Imaging Agents for Tumors

Radiolabeled anti-αVβ6 diabodies for use as molecular imaging agents for imaging αVβ6-positive tumors with positron emission tomography.

X-Ray Enhanced Polymerization Of Nanostructures And X-Ray Activated Release Of Ions From Nanostructures

A novel drug delivery system that is activated by low dose X-Ray which has further applications in imaging.

Device and Method for Measuring Beam Quality in CT

Researchers at the University of California, Davis have invented a device and methods for half-value layer (HVL) characterization in computed tomography (CT) to allow a medical physicist to measure the HVL of an X-ray system while the X-ray tube is rotating - that is, during its normal operation without the necessity to make the x-ray tube stationery.

Enhancement Of X-Ray Radiation Using Nanomaterials

New phenomenon of dynamic enhancement of chemical reactions by nanomaterials under hard x-ray radiation.

Method of Preparing Multivalent Single Chain Antibodies (scFv)

Construction of Multivalent Antibody scFv Through Cu(I) Catalyzed 1,3-Dipolar Cycloaddition

Targeted Delivery to the Heart Endothelium

Targeted Delivery of Nanoparticles to the Heart Endothelium with Large Pay-Load Potential, Applicable to Drug/Gene Delivery

Small Molecule Inhibitors of Amyloid-beta Protein Oligomers

Aβ-binding Small Molecules for Alzheimer's Disease Treatment and Imaging

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