A novel technology for real-time, non-invasive monitoring and adaptive control of electron radiotherapy treatments using acoustic signals.

This technology represents a pioneering approach to vaccine development, focusing on encapsulated adjuvants and antigens to enhance efficacy while minimizing side effects.

Introducing a groundbreaking orthogonal redox cofactor, NMN+, to revolutionize redox reaction control in biomanufacturing.

In magnetic resonance imaging (MRI) scanners, the detection of nuclear magnetic resonance (NMR) signals is achieved using radiofrequency, or RF, coils. RF coils are often equivalently called “resonance coils” due to their circuitry being engineered for resonance at a single frequency being received, for low-noise voltage gain and performance. However, such coils are therefore limited to a small bandwidth around the center frequency, restricting MRI systems from imaging more than one type of nucleus at a time (typically just hydrogen-1, or H1), at one magnetic field strength.To overcome the inherent restriction without sacrificing performance, UC Berkeley researchers have developed an MRI coil that can perform low-noise voltage gain at arbitrary relevant frequencies. These frequencies can be programmably chosen and can include magnetic resonance signals from any of various nuclei (e.g., 1H, 13C, 23Na, 31P, etc.), at any magnetic field strength (e.g., 50 mT, 1.5T, 3T, etc.). The multi-frequency resonance can be performed in a single system. The invention has further advantages in terms of resilience due to its decoupled response relative to other coils and system elements.

Precise control of wound healing depends on physician’s evaluation, experience. Physicians provide conditions and time for body to either heal itself, or to accept and heal around direct transplantations, and their practice relies a lot on passive recovery. Slow healing of recalcitrant wounds is a known persistent problem, with incomplete healing, scarring, and abnormal tissue regeneration. 23% of military blast and burn wounds do not close, affecting a patient’s bone, skin, nerves. 64% of military trauma have abnormal bone growth into soft tissue. While newer static approaches have demonstrated enhanced growth of non-regenerative tissue, they do not adapt to the changing state of wound, thus resulting in limited efficacy.

Advances in biological research have been greatly influenced by the development of organoids, a specialized form of 3D cell culture. Created from pluripotent stem cells, organoids are effective in vitro models in replicating the structure and progression of brain development, providing an exceptional tool for studying the complexities of biology. Among these, cortical organoids, comprising in part of neurons, have been instrumental in providing early insights into brain formation, function, and pathology. Functional characteristics of cortical organoids, such as cellular morphology and electrophysiology, provide physiological insight into cellular states and are crucial for understanding the roles of cell types within their specific niches. And while progress has been made studying engineered neuronal systems, decoding the functional properties of neuronal networks and their role in producing behaviors depends in part on recognizing neuronal cell types, their general locations within the brain, and how they connect.

Researchers at the University of California, Davis have developed an approach to combat Feline Infectious Peritonitis (FIP) through an in vitro-transcribed (IVT) RNA vaccine targeting the FCoV nucleocapsid (N) protein antigen.

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