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Retractable Step Cannula For Brain Delivery Of Therapeutics
An adjustable step cannula to minimize therapeutic agent leakage and maximize on-target drug delivery. This new cannula design improves brain drug delivery over current fixed-length step cannulas.
Method And System For Diagnosing And Training Cognitive Fitness Via Rhythmic Engagement
This invention is a novel method to diagnose and improve cognitive function through an adaptive training program that incorporates rhythmic engagement with computer-based game mechanics.
Novel Radiotracers for Imaging Glucocorticoid Receptor in Treatment-resistant Cancer Patients
UCSF researchers have invented novel radiotracers that allow imaging of glucocorticoid receptor (GR) expression using positron emission tomography (PET) in patients with treatment-resistant solid cancer, including prostate, breast, ovarian and lung cancer.
Automated Jugular Venous Pressure Measurement
The clinical exam for measuring jugular venous pressure (JVP), a measurement used to assess heart function has not substantially changed since the 1950s. This invention is a novel device to calculate JVP using accelerometers. This technology allows for more accurate and automated methods for measuring JVP, eliminating the need for a clinical exam.
A Novel Method to Generate Specific and Permanent Macromolecular Covalent Inhibitors
UCSF researchers have invented a novel method to generate covalent macromolecular inhibitors. This strategy allows a peptide inhibitor to bind to its target protein specifically and irreversibly through proximity-enabled bioreactivity.
Protein Kinase C Epsilon Small Molecule Inhibitors to Treat Pain, Anxiety, Alcoholism, and Nicotine Addiction
This invention provides new inhibitors to protein kinase C epsilon (PKCε) for the treatment and prophylaxis of various diseases such as pain, anxiety, alcoholism, inflammation, cancer, diabetes, and other conditions.
Magnetic: A Novel Algorithm for Identification of Cancer Therapeutics
Modular Analysis of Genomic NETworks In Cancer (MAGNETIC) is a novel algorithm that performs functional network analysis of molecular profiling data to identify tumor biomarkers and link them to therapies.
Method for fabricating micron-scale stepped needles intended for the insertion of devices
This invention is a novel method for fabricating needles with stepped ends. The method uses a brazing technique to achieve a fine stepped needle meant for delivering probes into tissue. This method creates needles strong enough to be used in neural surgery, but thin enough (<15 um) to create a very minimal entry wound.