Gasdermin-D Deficient Mice

Brief Description

UC researchers created a Gasdermin-D deficient mice that carry a CRISPR/Cas9-derived knock-out allele of the mouse Gsdmd gene that involves a 19 bp and a 1 bp (20 bp total) insertion in exon 2. 

Suggested uses

• used in studies of inflammasome/pyroptosis processes.