ABSTRACT: Stable cyclic (alkyl)(amino) carbenes as ligands for transition metal catalysts

ABSTRACT

Researchers at the University of California, Riversive have developed stable carbene ligands that  have a carbene center flanked by a quaternary carbon and an amino group, and having utility in the preparation of various catalysts.

The catalysts of the present invention are useful in catalyzing a variety of synthetic organic reactions including amine arylation reactions, Suzuki coupling reactions (aryl-aryl or aryl-alkyl coupling reactions), and α-arylation reactions. Still other reactions that can benefit from the above-noted complexes include, for example, hydroformylation (of alkenes and alkynes), hydrosilylation (of alkenes, alkynes, ketones and aldehydes), metathesis (olefin(RC, CM, ROM, ROMp) ene-yne), carbonylation, hydroarylation and hydroamination.

Patent Status