New Therapeutic Use of Existing Compounds to Treat Hearing Loss
Invention Novelty
This technology can effectively slow or prevent hearing loss by stabilizing calcium fluxes in and out of intracellular organelles using known compounds.
Value Proposition
Current treatments for hearing loss are medical devices such as cochlear implants or hearing aids. However, it is not curable or preventable by any medication. This invention provides a novel method to treat all forms of progressive hearing loss and deafness.
Technology Description
A researcher at the University of California, San Francisco has discovered existing compounds that are hypothesized to treat hearing loss caused by maladaptive intracellular signaling that leads to apoptotic cell death. The compounds are predicted to reduce the death of hair cells in the ear which is caused by aberrant activation of specific signaling pathways.
Stage of Development
Proof of concept
Data Availability
Under CDA/NDA
Related Materials
- Not available at this time
Patent Status
| Country | Type | Number | Dated | Case |
| United States Of America | Issued Patent | 11,957,655 | 04/16/2024 | 2016-033 |
| Canada | Published Application | 2016-033 | ||
| European Patent Office | Published Application | 2016-033 | ||
Additional Patent Pending
Contact
- Kathleen A. Wilson-Edell
- Kathleen.Wilson-Edell@ucsf.edu
- tel: View Phone Number.
Inventors
- Sherr, Elliott H.
Other Information
Keywords
Hearing loss, Compounds, Calcium flux