Imaging Guided Ablative Laser Surgery

Tech ID: 23934 / UC Case 2014-378-0

Abstract

Researchers at the University of California, Davis have devised an objective real-time method of visualizing the treatment area that will that will allow a laser surgeon to select appropriate ablative laser settings to treat a skin lesions and lesional tissues from other organ systems including, but not limited to: oral mucosa/gingiva, ear/nose and throat, esophagus, gastrointestinal, genitourinary, ophthalmologic and cardiopulmonary.

Full Description

Ablative laser surgeries, exploit the high energy, and defined focal point of lasers to vaporize tissue. Current clinical knowledge for assessing the treatment site prior to or post ablative laser surgery is limited. The settings used in ablative laser surgeries are often selected based on the laser surgeon’s selective clinical judgment, or based upon a sum of prior experiences. Current ablative laser therapy laser device settings are based upon 1) histology obtained from biopsy of the area of skin or other tissue to be treated several days or weeks in advance of the ablative laser therapy or 2) by the laser surgeon’s clinical judgment, based upon physical examination findings and previous experience with other patients with similar conditions, or a combination of the above. However, the precise depth of the skin or other tissue lesion is not always clear prior to surgery.

Researchers at the University of California, Davis have developed a novel method of ablative laser therapy using imaging of the target tissue region. The imaging would provide the basis for selecting the ablative laser therapy laser device settings. This method will allow surgeon’s to evaluate lesions prior to laser therapy and also post-laser treatment therapy to monitor healing and response to treatment. This objective real-time method of visualizing the treatment zone may assist laser surgeons in choosing the appropriate ablative laser settings.

Applications

  • Therapeutic uses where ablative laser therapy is used to treat various dermatalogical conditions such as moles, warts, photoaging, benign and malignant skin tumors, vascular lesions, skin scarring, and fibrosis
  • Dental conditions including: Gingival hyperplasia and other lesions treatable by ablative laser therapy
  • Ear/nose and throat conditions including polyps and other lesions treatable by ablative laser therapy
  • Ophthalmologic conditions including: eye-lid neoplasms basal cell carcinoma; papillomas and other lesions treatable by ablative laser therapy
  • Cardiopulmonary conditions and treatments including: Transmyocardial Laser Revascularization (TMR) and other conditions
  • Gastrointestinal and esophageal conditions including: Barrett's esophagus and other lesions treatable by ablative laser therapy
  • Genitourinary conditions including: condylomata, penile carcinoma, bladder and skin hemangiomata and other lesions treatable by ablative laser therapy

Features/Benefits

  • Non-invasive
  • Real-time high resolution imaging
  • Imaging of the skin or other organ tissue to select ablative laser treatment settings prior to laser surgery
  • Ability to evaluate treated sites immediately after treatment to confirm adequate removal of desired lesion tissue

Patent Status

Country Type Number Dated Case
United States Of America Published Application 20160317226 11/03/2016 2014-378
 

Contact

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Inventors

  • Jagdeo, Jared
  • Mamalis, Andrew D.

Other Information

Keywords

real-time, ablative laser theraphy, ablative laser surgeries, target tissue, laser settings

Categorized As