Monoclonal Antibodies Against GPIHBP1
Tech ID: 23751 / UC Case 2014-255-0
Innovation
Researchers at UCLA have developed monoclonal antibodies that recognize mouse and human glycosylphosphatidylinositol-anchored high density lipoprotein binding protein 1 (GPIHBP1).
- Rat monoclonal antibody, 11A12, against mouse GPIHBP1
- Mouse monoclonal antibody against human GPIHBP1
Background
Dietary fats are packaged by the intestines into triglyceride-rich lipoproteins called chylomicrons. The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LPL) along the luminal surface of capillaries, mainly in heart, skeletal muscle, and adipose tissue. GPIHBP1 is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons (Beigneux et al., 2007 [PubMed 17403372]).
Applications
Western, IHC, ICC
Related Materials
Contact
- UCLA Technology Development Group
- ncd@tdg.ucla.edu
- tel: View Phone Number.
Inventors
- Fong, Loren G.
- Young, Stephen G.
Other Information
Keywords
antibody, monoclonal, lipid, triglyceride, reagents, research tools
