A high quality nanometer scale electrical circuit with a single protein attached to a carbon nanotube that allows for the detailed study of the kinetics and dynamics of single proteins.
A robust method for non-covalently linking single biomolecules to an electrical circuit and reading biomolecular dynamics has been developed. This novel implementation utilizes carbon nanotubes and results in a very generalizable, high yield approach with an improved signal to noise ratio. This system also provides for a higher information content and more straightforward analysis than current approaches.
Drug discovery, protein studies
Highly generalizable, high yield method providing an improved signal to noise ratio
|United States Of America||Issued Patent||9,164,053||10/20/2015||2011-764|
Nanometer scale electrical circuit, Single protein dynamics, Drug discovery, Protein studies