Knockout Mice Deleting 2a Subunit of Sodium Channel

Tech ID: 21933 / UC Case 2002-230-0

Technology Description

A line of knockout mouse hase been developed that deletes the 2a subunit of the brain Na channel. This mouse model makes possible the modellingof a variety of neurologic disorders, drug target validation, and the screening of neuroactive drug candidates for efficacy, side effects and mechanism of action.


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University of California, San Diego
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