In collaboration with MIT, Researchers at the University of California, Davis have contributed to the development of an Integrated Opitcal Sampling Platform.

An engineered polymerase enabling the synthesis of threose nucleic acid (TNA) for advanced therapeutic applications.

A novel diagnostic technology offering rapid, accurate, and inexpensive detection, genotyping, and quantification of viral RNA in patient-derived samples, enhancing public health capabilities.

Glaucoma is a leading blinding disease affecting at least 60 million people worldwide. A major risk factor for glaucoma is high intraocular pressure (IOP), which can damage the optic nerve and cause permanent blindness without treatment.  UC researchers have found that Schlemm’s canal (SC) is a critical structure involved in aqueous humor drainage and IOP regulation and have found certain receptors that are expressed on SC.  The researchers are working to develop several molecules that can be targeted or modulated to regulate SC function to treat glaucoma.  

A novel technology for real-time, non-invasive monitoring and adaptive control of electron radiotherapy treatments using acoustic signals.

This technology represents a pioneering approach to vaccine development, focusing on encapsulated adjuvants and antigens to enhance efficacy while minimizing side effects.

Introducing a groundbreaking orthogonal redox cofactor, NMN+, to revolutionize redox reaction control in biomanufacturing.

In magnetic resonance imaging (MRI) scanners, the detection of nuclear magnetic resonance (NMR) signals is achieved using radiofrequency, or RF, coils. RF coils are often equivalently called “resonance coils” due to their circuitry being engineered for resonance at a single frequency being received, for low-noise voltage gain and performance. However, such coils are therefore limited to a small bandwidth around the center frequency, restricting MRI systems from imaging more than one type of nucleus at a time (typically just hydrogen-1, or H1), at one magnetic field strength.To overcome the inherent restriction without sacrificing performance, UC Berkeley researchers have developed an MRI coil that can perform low-noise voltage gain at arbitrary relevant frequencies. These frequencies can be programmably chosen and can include magnetic resonance signals from any of various nuclei (e.g., 1H, 13C, 23Na, 31P, etc.), at any magnetic field strength (e.g., 50 mT, 1.5T, 3T, etc.). The multi-frequency resonance can be performed in a single system. The invention has further advantages in terms of resilience due to its decoupled response relative to other coils and system elements.