Compounds to Treat Citrus Huanglongbing

Tech ID: 31942 / UC Case 2020-237-0

Background

Citrus greening disease also known as Huanglongbing disease (HLB), has no known cure and causes citrus crop damage worldwide. Management of this disease is expensive and has resulted in annual losses of approximately $1.2 billion dollars in the state of Florida alone. This disease is caused by the gram negative bacterium Candidatus Liberibacter (CLas), and the bacterium’s insect transmission vector is the Asian citrus psyllid.

Current strategies of HLB management include chemical treatment against the psyllid vector, identification and removal of infected trees and the use of pathogen-tested citrus nursery stocks for replants in new orchards. A treatment for HLB is desirable in citrus that would not require the destruction of infected trees.

Roper21

Fig 2: The effect of Huanglongbing (citrus greening) on citrus fruit

 

Brief Description

Prof. Caroline Roper and her colleagues from the University of California, Riverside and Point Loma Nazarene University have identified compounds that may be used to inhibit CLas growth and thereby treat HLB in citrus crops. This technology has the potential to be an economical and effective treatment for HLB infected trees.

Suggested uses

  • Compounds to treat HLB affected trees infected by CLas bacteria by inhibiting bacterial growth

Patent Status

Country Type Number Dated Case
United States Of America Published Application 2023010237 03/30/2023 2020-237
 

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Keywords

Huanglongbing disease, Huanglongbing, HLB, citrus greening, small molecule, citrus, treatment

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