Bioresorbable Electrodes for Recording, Stimulation, and Drug Delivery

Tech ID: 30616 / UC Case 2018-283-0

Background

Neural electrodes have been widely used for monitoring neural signals and for delivering electrical stimulation to treat injuries and disorders. Current electrodes are mostly fabricated from stiff inert conductive metals like platinum and stainless steel. The mechanical mismatch between these metals and neural tissues contributes to tissue damage and fibrosis, or the formation of extra connective tissue. After implantation these metallic implants experience performance deterioration due to biofouling and tissue damage. There is a need for implantable neural electrodes that can easily be absorbed by the body without surgical removal.

Brief Description

Prof. Huinan Liu and her colleagues from the University of California, Riverside have developed new magnesium based bioresorbable electrodes capable of recording, stimulating, and repairing neural tissues for a wide range of diseases and injuries. These new electrodes degrade naturally in aqueous physiological environments and eliminate the need for surgical removal of the implanted electrodes. This technology would benefit both doctors, patients, and researchers by introducing a new generation of neural electrodes that minimize damage to neural tissue while providing the option of drug delivery with the conductive polymer coating.

Applications

  • Bioresorbable electrodes capable of recording and delivering electrical signals and drugs for tissue stimulation and repair
  • Use of the electrodes for the repair of neural tissue for a wide range of diseases and injuries, such as epilepsy, Parkinson’s disease, and spinal cord injuries

Patent Status

Country Type Number Dated Case
Patent Cooperation Treaty Published Application 2019152415 08/08/2019 2018-283
 

Additional Patent Pending

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