Methods of Diagnosing Ocular Diseases

Tech ID: 29806 / UC Case 2013-428-0


Researchers at UCLA have developed a novel technique to detect ocular diseases.


The ophthalmic device market is expected to grow to $58.44 billion by 2023. Diseases of the eye often stem from perturbations in the homeostatic rate of cell turnover, and the process by which cell death occurs may affect cellular response of surrounding cells and induce premature incidence. Current diagnostic practices for these diseases are limited to relying on patient response and technologies with low sensitivity. These detection constraints delay diagnosis and prevent accurate tracking of disease progression.


Kwong and colleagues have developed an innovative method to diagnose and chart the progression of ocular diseases by live, in vivo imaging. Molecular factors involved in cell death are labeled locally and monitored using state-of-the-art non-invasive imaging techniques. The improved tracking ability enables closer monitoring of response to therapy and increased understanding of disease towards improved therapeutics.


  • Tracking of ocular diseases progression – Glaucoma, Neuropathies 
  • Early diagnosis of ocular diseases


  • Live, in vivo monitoring 
  • Local or topical administration

State Of Development

This technique has been validated in experimental models.

Patent Status

Country Type Number Dated Case
United States Of America Published Application 20150367004 12/24/2015 2013-428


Learn About UC TechAlerts - Save Searches and receive new technology matches


  • Kwong, Jacky M.K.

Other Information


Ocular Diseases, Diagnostics, Therapeutics, Medical

Categorized As