Nanoscale Optical Voltage Sensors
Tech ID: 25902 / UC Case 2016-298-0
UCLA researchers have developed a novel nanoscale optical voltage sensor.
UCLA researchers have developed nanoscale optical voltage sensor. The hybrid structure of the sensor allows active manipulation of light signals at sub-wavelength scale. NOVS can sensitively and rapidly transduce membrane voltage signals into detectable optical signals for direct recording and monitoring.
- Nanoscale electro-optics
- Information displays
- In vitro and in vivo voltage sensors for highly sensitive real-time monitoring cellular membrane potential
- In situ monitoring of local electric fields
- Monitoring of voltage propagation in neurons
- Neuronal and brain mapping
- Real time modulation of plasmonic resonance.
- Enable creations of a new generation of nanoscale voltage sensors
- Larger voltage sensitivity detection and mapping capabilities of neuronal electrophysiological signals and brain function connectivity
- High sensitivity, resolution, and throughput
- Can be flexibly delivered into living tissue via the vascular system and minimally invasive probes
- Can be expanded in detecting, imaging, monitoring and manipulating neuronal activity
State Of Development
The invention has been successfully prototyped and demonstrated.