Investigators at University of California, Berkeley have identified a hybridoma cell line that produces monoclonal antibodies with specificity for the Vg3 chain of the mouse T cell antigen receptor complex. This gene product is is expressed only in the early fetal thymus. In the adult mouse, Vg3 expression appears to be limited to Thy-1+ cells in the epidermis.
References:
Havran et al. 1989. PNAS 86:4185-9
Havran & Allison 1988 Nature 335:443-5
antibody, research tool