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SFK Covalent Protein Genetic Engineering Platform: Unlocking Potent Therapeutics for Undruggable Targets
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Rapid Diagnostic Platform for Stratifying Cancer Patients with Immunoresponsive ‘Cold’ Tumors via TGFß Signaling and DNA Damage Response
A Fluorescent-Labeled Phage Display Platform: RAPID and BIAS Technologies Transform Antibody Discovery for Therapeutic Development
Protein Engineering with Phosphorus Fluoride Exchange (PFEx): A Novel Click Chemistry Approach for Biotherapeutics and Proteomics
Novel Molecular Glues Targeting 14-3-3/ER for Treatment-Resistant ER+ Breast Cancer
Next-Generation CRISPR-Barcoded Organoid-Mouse Models for Prostate Cancer Drug Discovery and Immunotherapy Research
RocASO: A Breakthrough Platform to Silence Undruggable RNA Targets and Transform Therapeutics
Precision Oncology Diagnostic: Epithelial-to-Mesenchymal Transition Gene Signature Technology for Metastasis Prediction and Personalized Cancer Care
Cell Type-Selective, Potent Signaling Pathway Modulation Using A Guide-Effector Bispecific Design
Manipulation Of Internalization Property Of Cell Surface Molecules Using A Guide-Effector Bispecific Design
Immune Impact Of Cyclic STAT3 Decoy Therapy
Covalent Chemical Inhibitors Of The Oncoprotein K-Ras (G12R)
Discovery Of Kras G12c Inhibitor-Specific Antibodies For Oncogene-Specific Chemically-Directed Immune Targeting
Collimated Compton Camera
Induced Synthetic Intracellular Cytokine And Growth Factor Circuits For Cell Autonomous Control Of Cell Signaling, Proliferation, Survival And Cell State
A Predictive ML Model For Cancer Early Relapse
Methods Of Treating Stat1 Dependent Cancer
Inhibitors Of P90 Rsk
Autologous Irradiated Whole Cell Tumor Vaccines Lentivirally Engineered To Express Cd-80, Il-15 And Il-15 Receptor Alpha
Identification Of Selective Regulators Of Oncogene Translation
Optimization Of Lead Small Molecule Inhibitors Of Taspase1 For Cancer Therapeutics
Genomic Destructive CRISPR Guide RNAs
AAV-Based Gene Therapy for Glioblastoma Treatment Using Interferon Cytokines
Enhancing Cancer Immunotherapy with Modified Adaptor Protein and CAR-NK Cell Technology
Next-Generation Monoclonal Antibody Therapy Targeting High-Risk Tumors