Approach in optical spectroscopy for the detection of ischemic tissue injury
Several novel and distinct approaches to detect and quantify ischemic tissue damage have been developed by researchers at the University of California, Davis and the Lawrence Livermore National Laboratory (LLNL). Currently, physical examination and tissue biopsy remain the principal means of determining the viability of tissue that may be suffering from inadequate blood supply. Although symptoms of ischemic tissue damage are clinically relatively easily identified once they have occurred, significant problems prevent the detection of these symptoms in time to prevent permanent damage:
There is a substantial need to develop means of detecting and quantifying ischemic tissue damage in its early stages, before it is clinically apparent and before irreversible damage has occurred.
This UC Davis and LLNL invention provides novel optical spectroscopy methods to quantify ischemic tissue and organ injury. These methods are non-invasive, non-traumatic, portable, and can make measurements in a matter of seconds. In addition, these methods can be realized through fiber optic probes, making it possible to take measurements of target organs deep within a patient’s body.
Country | Type | Number | Dated | Case |
United States Of America | Issued Patent | 7,587,236 | 08/19/2009 | 2004-313 |
optical spectroscopy, ischemic tissue injury, clinical diagnostic, non-invasive, portable