A method is provided to prepare a one or more or a plurality microfluidic channels on a receptive material, comprising the steps of a) applying an image-forming material to a heat sensitive thermoplastic receptive material, also referred to as thermoplastic material, in a designed pattern, b) heating said material under conditions that reduce the size of the thermoplastic receptive material, also referred to as thermoplastic material, material by at least about 60%, and c) preparing the microfluidic channels via lithography. In an alternative aspect, the microfluidic channels are created by lithography on the image-formed, heat-reduced thermoplastic material.
Also provided herein is a method to prepare one or more or a plurality of microfluidic channels on a receptive material by etching a designed pattern into a heat sensitive thermoplastic material support and then heating the material under conditions that reduce the size of the thermoplastic receptive material, also referred to as thermoplastic material, material by at least about 60%.
The receptive materials prepared by this method are further provided for the fabrication of various devices to be used in applications such as biological and chemical processing and analysis, micro-mixers, which are necessary for biochemical reactions, chemical synthesis, and biological processes such as biochemical detection involving hybridization analyses, immunoassays, and cell-molecule interactions, near-field optical microscopy, sub-wavelength photonics, biochemical sensing, molecular detection, optical devices, filters and sorters, high-surface area conductors and actuators and solar energy harvesting. Methods of using such devices are also provided herein.
|United States Of America||Issued Patent||9,522,820||12/20/2016||2008-341|
Additional Patent Pending