Biomimetic Interfaces For Biodegradable Metallic Implants

Tech ID: 30592 / UC Case 2012-115-0


Metal implants made from titanium or steel are commonly used to align fractured bones to ensure proper healing.  However surgical removal of the metal hardware for internal fixation of broken bones may lead to complications and additional costs. The biodegradability of magnesium (Mg) and its alloys is advantageous and desirable for medical implants that only serve temporary functions during tissue healing.

Brief Description

Prof. Huinan Liu and her colleagues from the University of California, Riverside have developed a novel material that may be used for bioresorbable implants.  The degradation rate of Mg and its alloys in the materials are controlled through the use of a functional nanocomposite coating. Nanophase ceramic/polymer composite coated Mg provides promising properties and nano-scale surface features for the use as the next-generation biodegradable implant materials. This technology would benefit both doctors and patients, as orthopedic devices made of these materials would eliminate the need for implant removal surgery.

Liu 21

Fig. 1A An SEM image of a PLGA coated Mg substrate

Fig. 1B An SEM image of a nHA/PLGA coated Mg substrate


Suggested uses

  • This bioresorbable material may be used for the fabrication of orthopedic devices (i.e. plates, screws, and intramedullary nails)

Patent Status

Country Type Number Dated Case
United States Of America Published Application 20160206788 07/21/2016 2012-115

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Other Information


Magnesium alloy, biodegradable, implant, nanophase ceramic, polymer

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