Researchers from UC San Diego designed a wireless, fully-integrated, miniature “BioMote” microelectrode electrochemical sensor array that can be injected through a 16-gauge syringe for continuous, for long-term monitoring of analytes.
The low-power multi-technique potentiostat supports both amperometric and potentiometric techniques achieving 2.5 nA sensitivity with 30.1 dB dynamic range and 0.5 mV sensitivity with 43 dB dynamic range, respectively. The measurements are transmitted to a wearable device through backscatter using a self-oscillating current-to-frequency (I-to-F) converter. The system is wirelessly powered via the coupling between an on-chip 4-turn coil and a wearable device at 985 MHz. The self-contained 0.85×1.5 mm2 chip is implemented in 65 nm CMOS and consumes 970 nW.
One example would be the continuous monitoring of biomolecules in the interstitial fluid.
UC San Diego is actively soliciting companies interested in leveraging this patent-pending technology for biosensing applications other than alcohol.