UCLA researchers in the Department of Bioengineering have developed a novel electrical charge cancellation scheme to effectively remove residual charge on an electrode, achieving greater precision for lesser hardware cost, while maintaining a surgically implantable small size without extra pulse insertion.
Functional electrical stimulation is a method adopted by many biomedical implants to restore function to tissues in the human body. This technique involves stimulating tissue with an electrical current to evoke action potentials across neurons. Balancing charge is critical for the safe implementation of the respective implants, since a net residue charge can severely damage tissue and the electrodes. Current solutions for balancing charges have been suboptimal due to their limited precision in amplitude and time, requirement of a large capacitor, or need for extra balancing pulses to raise effectiveness. However, these methods can raise safety concerns, further supporting the need for a calibration method with increased precision within a compact size.
UCLA researchers have developed a novel electrical charge cancellation scheme to effectively remove residual charge on the electrode by precisely controlling either the width of the anodic or cathodic current stimulus. This approach doesn’t require additional short pulses, which are required for a DC capacitor, and allows for high precision net charge and timing control without increasing hardware size. Furthermore, this scheme is effective even if Warburg resistance is significant.
|United States Of America||Issued Patent||9,700,724||07/11/2017||2013-304|
charge balancing, circuit, neural stimulation, residual charge, pulse insertion, electrode array, electrode tissue interface, surgical implant, implantable device