Researchers at the University of California, Davis have developed a non-invasive, interference-based, optical device for blood flow monitoring. This technology is distinct from Diffuse Correlation Spectroscopy (DCS) and can be used alone, or to enhance conventional near-infrared spectroscopy (NIRS) oximetry, by providing information about flow supply.
Steady cerebral blood flow (CBF) is required for normal brain function. Continuous monitoring of CBF in humans in natural environments, however, is currently impractical. Conventional Diffuse Correlation Spectroscopy (DCS) is used to measure CBF but relies on light particle (photon) counting technology to detect blood flow. This costs several thousand dollars per detector, and is susceptible to ambient light noise.
Researchers at the University of California, Davis , have developed a low-cost portable near-infrared light-based (optical) sensor to monitor CBF continuously and noninvasively. This “Interferometric Diffusing Wave” (iDWS) technology uses complementary metal–oxide–semiconductor (CMOS) cameras, widely found in cell phone cameras and other mass-produced devices, to replace expensive optical CBF detectors. By using interferometry, each CMOS camera pixel is used as a detector for fluctuations of light. These fluctuations can be used to detect blood flow in the brain. The numerous pixels also negate problems associated with photon counting as each CMOS camera pixel can behave as an independent detector, making the CBF reading resistant to ambient light.
|Patent Cooperation Treaty||Published Application||2019204231||10/24/2019||2018-635|
Additional Patent Pending
diffuse, correlation, spectroscopy, diffusing wave spectroscopy, near-infrared spectroscopy, non-invasive imaging, blood flow, tissue optics, dynamic light scattering, diffuse correlation spectroscopy, DCS, NIRS, oximetry, interferometric diffuse wave spectroscopy, iDWS, CMOS,