Topical Anti-proliferative Agents for Melanoma

Tech ID: 29464 / UC Case 2018-181-0

Patent Status

Patent Pending

Brief Description

Due to the year-to-year increase in skin cancer incidences and dramatic decrease in survival, once the melanoma has metastasized, a preventative treatment for skin cancer would be significant. Currently, the only defenses against melanoma are applying sun protection factor (SPF) regularly and protecting oneself from direct sun exposure. In a 2015 national survey conducted by the Center for Disease Control and Prevention (CDC), 34% of adults reported using SPF 15 or higher and 35% of adults reported having a sunburn in the past year. 


UC Berkeley researchers have discovered active antiproliferative compounds that can be applied post-sunburn to prevent the growth and metastases of melanoma and therefore, could reduce the number of melanoma incidences per year. Based on preliminary data, they are developing a compound cocktail composed of active lead compounds to develop an anti-proliferative and cytostatic topical treatment of melanoma to slow down tumor development. 

Suggested uses

  • Treatment for skin cancer



  • Beneficial for patients with long surgical intervals or during the time when medical interventions are not immediately available


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  • Firestone, Gary Lee

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