Transporter for Cyclic Dinucleotide

Tech ID: 29212 / UC Case 2018-108-0

Patent Status

Country Type Number Dated Case
United States Of America Published Application 20210275547 09/09/2021 2018-108
European Patent Office Published Application 3794010 03/24/2021 2018-108
Patent Cooperation Treaty Published Application WO2019222500 11/21/2019 2018-108
 

Brief Description

The inventors have identified the transporter protein SLC19A1 for transport of the cyclic dinucleotide ADU-S100 into cells in culture. The invention can be used for enhancement of ADU-S100 uptake by cells. ADU-S100 is a clinical compound for immunotherapy of cancer. It can also be used for predicting which patients will respond better to ADU-S100.

Suggested uses

  • Identifying patients who will respond better to therapy. 
  • Identifying drugs to combine with ADU-S100 therapy to improve efficacy in treating cancer.

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Inventors

  • Raulet, David H.

Other Information

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