Self-Calibrating Hollow Microneedles

Tech ID: 28867 / UC Case 2017-044-0

Brief Description

A new approach for building self-calibrating hollow microneedles that can be transferred to an electronic die or other substrates.

Background

Transdermal drug delivery has become a commonly practiced technique for delivering vaccinations and drugs into the human body. However, many drugs cannot be delivered using this method. The use of microneedles in transdermal drug delivery expand the number of medications that can be delivered while improving upon pain level and increased accuracy. Numerous methods of creating hollow microneedles exist however none of the current approaches address many challenges including painful skin penetration, tip sharpness, or the bevel and metal coating.

Description

Researchers at the University of California, Santa Barbara have created a new approach for building self-calibrating hollow microneedles that can be transferred to an electronic die or other substrates. This unique method results in a microneedle with an extremely sharp and beveled tip. Other advantages include individual addressability and the ability to be functionalized. Additionally, this approach includes a built-in volume calibration to ensure measurement and dispensing accuracy regardless of volume. While microneedles are typically a more expensive option for drug delivery, this approach requires fewer manufacturing steps reducing cost and improving yield.

Advantages

  • Bevel and sharp tip
  • Ability to be transferred to other metal substrates
  • Fewer manufacturing steps reducing cost and improving yield
  • Calibration free sensing platform
  • Ability to accurately measure volume

Applications

  • Transdermal drug delivery for medications, vaccinations, insulin, etc.
  • Diagnostic devices

Patent Status

Patent Pending

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Inventors

  • Kim, Hyunjin
  • Theogarajan, Luke

Other Information

Keywords

microneedles, transdermal drug delivery, drug delivery, indpharma, self calibrating, hollow, hollow microneedles, medications, medicine, insulin, vaccinations, diagnostics, diagnostic devices

Categorized As

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