OCE (Optical Coherence Elastography) and ARF (Acoustic Radiation Force) for blood coagulation assessment.
Diagnostic tool for assessing the clot formation/dissolution kinetics and strength.
Most commonly, routine laboratory based coagulations tests (prothrombin time/activated partial thromboplastin time, fibrinogen levels and platelet numbers are used to assess the patient’s current coagulation status. The tests are of limited value in rerioperative and acutely ill patients because of delay in transportation and centrifugation. Turnaround time is often too long for the tests to be reliable. This invention uses an optical approach an acoustic radiation force based optical coherence elastography to rapidly assess the dynamic whole blood coagulation by measuring the elastic properties of blood during coagulation. The potential applications of this invention include diagnosis and treatment management for bleeding patients in a variety of clinical situations in real-time at point of care.
|United States Of America||Issued Patent||10,365,254||07/30/2019||2016-273|