This technology can effectively slow or prevent hearing loss by stabilizing calcium fluxes in and out of intracellular organelles using known compounds.
Current treatments for hearing loss are medical devices such as cochlear implants or hearing aids. However, it is not curable or preventable by any medication. This invention provides a novel method to treat all forms of progressive hearing loss and deafness.
A researcher at the University of California, San Francisco has discovered existing compounds that are hypothesized to treat hearing loss caused by maladaptive intracellular signaling that leads to apoptotic cell death. The compounds are predicted to reduce the death of hair cells in the ear which is caused by aberrant activation of specific signaling pathways.
Proof of concept
|European Patent Office||Published Application||2016-033|
|Patent Cooperation Treaty||Reference for National Filings||WO2017074830||05/04/2017||2016-033|
Additional Patent Pending