New Therapeutic Use of Existing Compounds to Treat Hearing Loss

Tech ID: 25575 / UC Case 2016-033-0

Invention Novelty

This technology can effectively slow or prevent hearing loss by stabilizing calcium fluxes in and out of intracellular organelles using known compounds.

Value Proposition

Current treatments for hearing loss are medical devices such as cochlear implants or hearing aids. However, it is not curable or preventable by any medication. This invention provides a novel method to treat all forms of progressive hearing loss and deafness.

Technology Description

A researcher at the University of California, San Francisco has discovered existing compounds that are hypothesized to treat hearing loss caused by maladaptive intracellular signaling that leads to apoptotic cell death. The compounds are predicted to reduce the death of hair cells in the ear which is caused by aberrant activation of specific signaling pathways.

Stage of Development

Proof of concept

Data Availability

Under CDA/NDA

Related Materials

  • Not available at this time

Patent Status

Country Type Number Dated Case
Canada Published Application 2016-033
European Patent Office Published Application 2016-033
Patent Cooperation Treaty Reference for National Filings WO2017074830 05/04/2017 2016-033
 

Additional Patent Pending

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Inventors

  • Sherr, Elliott H.

Other Information

Keywords

Hearing loss, Compounds, Calcium flux

Categorized As