Monoclonal Antibody against ATR-IP (Clone 11)

Tech ID: 25196 / UC Case 2011-384-0

Brief Description

Mouse monoclonal antibody against the human ATR-interacting protein (ATR-IP). This antibody has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Full Description

This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012.

The described mouse monoclonal IgG1 antibody binds to human ATR-IP and has been described for use in immunocytochemistry/immunofluorescnece, immunoprecipitation, and western blot.

Suggested uses

Immunocytochemistry/immunofluorescence

Immunoprecipitation

Western blot

Advantages

Specific antibody to detect ATR-IP by antibody-antigen complex formation.

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Inventors

  • Kim, Yoon
  • Lee, Eva Y H P

Other Information

Keywords

Monoclonal antibody, Centrosomal protein 164kDa, Cep164, Immunocytochemistry/immunofluorescence, Immunoprecipitation, Western blot

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