It is difficult to produce a conformal coating of complex 3D surfaces. Especially challenging is the problem of depositing biologically active layers such as cell-laden collagen that cannot be sprayed (shear stress damages the cells) or brushed across a surface (the collagen layer will not coat the surface uniformly). Additionally, other techniques do not ensure a smooth surface with uniform layer thickness.
Researchers at the University of California, Irvine, Drs. Kheradvar and Kulinsky, have developed a device and method that allows for conformal coating of complex 3-dimensional surfaces. In particular, this device and method promote the coating of cells and biological materials like collagen onto surfaces for biomedical applications and tissue engineering.
This is a mask-free technology that may be used to coat scaffolds used for tissue or organ engineering.
|United States Of America||Issued Patent||10,245,614||04/02/2019||2015-224|