Metabolic Engineering Of Anaerobic Fungal Pathways For The Production Of Biofuels And Antimicrobial Compounds

Tech ID: 23730 / UC Case 2014-025-0

Brief Description

A novel method of manipulating metabolic networks and pathways within anaerobic gut fungi for their use in the production of lignocellulose-degrading enzymes and novel polyketide synthases (PKSs).

Background

Anaerobic gut fungi show great potential for metabolic engineering applications. Their natural products include ethanol and hydrogen (of chief interest for biofuels) and putative anti-microbial compounds (i.e. antibiotics and antimycotics). Thus far, anaerobic gut fungi have remained completely unexplored regarding these potential applications.

Description

Researchers at the University of California, Santa Barbara have developed a novel method of manipulating metabolic networks and pathways within anaerobic gut fungi for their use in the production of lignocellulose-degrading enzymes and novel polyketide synthases (PKSs). The novel enzymes can be used in the degradation of lignocellulose (plant biomass), production of biofuels and novel products, and production of antimicrobial compounds.

Advantages

  • Production of novel polyketide synthases (PKSs)
  • Production of unique cellulose-degrading enzymes (cellulases)


Applications

  • Biofuel production and bioremediation
  • Anti-microbial compound development
  • Drug discovery


Patent Status

Patent Pending

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Inventors

Other Information

Keywords

antimicrobial, PKS, biofuels, indpharma, indenergy, indadvmat

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