Asymetric Electrophilic Fluorination Using An Anionic Chiral Phasee-Transfer Catalyst

Tech ID: 23405 / UC Case 2012-047-0

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 9,981,977 05/29/2018 2012-047
 

Brief Description

The invention is a novel family of chiral catalysts for electrophilic addition reactions especially for fluorination.  The catalysts are salts including a chiral anionic component a a cationic component.  They are chiral, non-racemic compounds that function as phase transfer catalysts in certain asymmetric synthetic organic transformations.

Suggested uses

The ability to selectively transform a prochiral center in a compound to an enantiomerically enriched or enantiomerically pure chiral center has broad application, especially in the agricultural, pharmaceutical and polymer industries.

Advantages

Transform a prochiral center in a compound to an enamtiomerically enriched or enantiomerically pure chiral center.

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Inventors

  • Toste, Francisco D.

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