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Diagnostic Markers to Distinguish Between Squamous Cell Carcinoma and Pseudoepitheliomatous Hyperplasia

UCLA scientists have developed a novel diagnostic kit to reliably distinguish squamous cell carcinoma (SCC) from pseudoepitheliomatous hyperplasia (PEH). This fast diagnostic test can replace the non-quantitative and subjective diagnostic methods currently used in hospitals.

Fully Human Antibodies and Fragments Recognizing c-Met

UCLA researchers in the Department of Molecular and Medical Pharmacology have developed several novel recognition sequences against the human oncogene c-MET. These unique sequences are the basic building blocks used to make intact human antibodies and antibody fragments that can be conjugated to various payloads endowing them with great therapeutic and diagnostic potential in vitro and in vivo.

Diagnostic, Prognostic and Therapeutic Uses of Non-Coding RNAs in Leukemia

The Rao group at UCLA has developed a method of using lincRNA expression levels as a diagnostic and prognostic tool for B acute lymphoblastic leukemia. Furthermore, regulation of certain leukemia-associated lincRNA may hold therapeutic potential.

Homogenous Entropy-Driven Biomolecular Assay (HEBA)

Professors in the UCLA Department of Bioengineering have developed a novel short oligonucleotide assay to fluorescently detect biomolecules.

Novel Monoclonal Antibodies against Neospora Caninum

UCLA researchers have developed a large number of highly specific monoclonal antibodies against the intracellular parasite Neospora caninum that can be used for diagnostic or research purposes.

Wide-Field Imaging Of Birefringent Crystals In Synovial Fluid Using Lens-Free Polarized Microscopy For Crystal Arthropathy Diagnosis

UCLA researchers in the Department of Electrical Engineering have developed a new diagnostic tool for arthropathic diseases, such as gout.

Biologically Applicable Water-Soluble Heterogeneous Catalysts For Parahydrogen-Induced Polarization

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method of parahydrogen-induced polarization in water using heterogeneous catalysts.

Non-invasive Optometric Medical Diagnostic Device

UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a non-invasive, fast, low-cost optometric device that monitors changes in skin proteins to pre-screen diseases such as diabetes and skin cancer.

Trauma-released Proteins and Breakdown Products for Diagnosing Injury Severity, Pharmacokinetic Monitoring and Outcome Prediction in Neurotrauma Patients

UCLA researchers have identified a novel panel of neurotrauma biomarkers to diagnose traumatic brain injury (TBI), spinal cord injury (SCI) and concussions.

Genetic Mechanisms Of Resistance To Anti-Pd-1/L1

UCLA researchers have identified a rare genetic mutation in the interferon receptor signaling pathway that can be used as a diagnostic to predict whether a patient will be or has become resistant to a cancer immunotherapy.

NMR Probe for the Detection of Microstructures

UCLA researchers in the Department of Chemistry and Biochemistry have developed an NMR probe with superior sensitivity for in vivo spectroscopy and detection of ultra small samples.

Multi-Modal Depth-Resolved Tissue Status And Contact Pressure Monitor

Researchers in the UCLA Bioengineering Department have developed a device to detect changes in blood oxygenation of neonate intestines to allow for diagnosis of necrotizing enterocolitis.

Noninvasive Screening for Gestational Diabetes

Dr. Brian Koos in the Department of Obstetrics and Gynecology at UCLA has developed a noninvasive and accurate screening technology to identify gestational diabetes during early pregnancy. 

The Use of Voltammetry Based Assessment of Neurotransmitters and Metabolites in Vivo

UCLA researchers in the Departments of Medicine, Radiology and Bioengineering have developed novel methods for monitoring cardiac autonomic function in vascular and tissue compartments by measuring neurotransmitters and metabolites in vivo.

Method for Screening Delta Opioid Receptor Modulators

Dr. Christopher Evans, Director of the Brain Research Institute at UCLA, and colleagues have developed a screening methodology for identifying modulators of the delta opioid recepto

Enhanced Fluorescence Readout And Reduced Inhibition For Nucleic Acid Amplification Tests

UCLA researchers in the Department of Bioengineering have developed an enhanced fluorescent detection method for nucleic acid amplification tests.

Vectors for Antibody Expression

Brief description not available

Wireless Wearable Big Data Brain Machine Interface (W2b2/Wwbb)

UCLA researchers have developed a wireless wearable big data brain machine interface. This technology provides a user-friendly brain machine interface system that can monitor/record a large amount of brain activities and transfer, wirelessly, the processed/raw data to a remote mobile unit.

Predictive Markers for Dasatinib to Treat Solid Tumors

Investigators at the UCLA Geffen School of Medicine have identified potential markers to predict the response of breast cancer patients to dasatinib, an oral multi-kinase SRC/ABL inhibitor. There is potential to use these markers in the clinical development of dasatinib and other SRC kinase inhibitors that treat solid tumors.

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