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A Self-Regenerative Hybrid Tissue Structure For 3D fabrication of heart valves, blood vessels and other constructs / Mesh enclosed tissue constructs

Current tissue engineered constructs face drawbacks such as structural vulnerability, functionality, and a lack of mechanical properties. A continual need for a tissue constructs that can resist the physiological forces within the body, while being biocompatible, persists. Researchers at UC Irvine have developed a tissue construct composed of a multi-layered tissue enclosed on a metal mesh that addresses the drawbacks experienced by other developed solutions.

Efficient Nebulizer

Brief description not available

Method For Fabricating Two-Dimensional Protein Crystals

2D crystalline materials possess high surface area-to-volume ratios, light and can be very porous. These properties have rendered synthetic 2D materials immensely attractive in applications including electronics, sensing, coating, filtration and catalysis. The rational design of self-assembling 2D crystals remains a considerable challenge and a very active area of development. The existing methods for the bottom-up fabrication of biological or non-biological 2-D crystalline materials are not generalizable and scalable. 2D protein design strategies, in particular, require extensive computational work and costly protein engineering. In addition, these strategies have low success rates, the resulting materials contain large defects, and are multi-layered and therefore not appropriate for scaling or materials-applications. Moreover, these strategies often require the presence of lipids for supported assembly.

Oxidative CH Activation of Non-Activated Alkanes Using Metal-Organic Frameworks (MOFs) as Catalysts

UCLA researchers in the Department of Chemistry and Biochemistry have developed two novel organic framework-based catalysts used in CH activation during the process of converting methane into acetic acid. These catalysts demonstrate high efficiency and specificity, combined with the great chemical stability and reproducibility seen with organic framework materials.

Design and Synthesis of New Metal-Organic Frameworks (MOFs) With Unique Topologies

UCLA researchers in the Department of Chemistry and Biochemistry have developed a series of Metal-Organic Frameworks (MOFs) with unique topologies, structures, and pore sizes, thereby, making these materials more versatile in applications such as gas storage and separation.

Catalytic Coupling Reactions Using Frameworks With Open-Metal-Sites

UCLA researchers in the Department of Chemistry and Biochemistry have developed a group of novel organic framework-based catalysts used in coupling reactions. These catalysts demonstrate high efficiency and specificity, combined with the great chemical stability and reproducibility seen with organic framework materials.

Reversible Ethylene Oxide Capture in Metal Organic Frameworks (MOFs)

UCLA researchers in the Department of Chemistry and Biochemistry have devised a method to separate and purify gases such as ethylene oxide from gaseous mixtures using functionalized and porous metal-organic, covalent-organic, and zeolitic-imidazolate frameworks.

Reversible Hydrogen Storage Using Metal-Organic Frameworks (MOFs)

UCLA researchers in the Department of Chemistry and Biochemistry have demonstrated the ability of functionalized zeolitic imidazolate frameworks (ZIFs) and covalent organic frameworks (COFs) to store significant amounts of hydrogen gas in a safe and practical manner, with ten-fold greater storage capacity compared to other methods.

Adsorptive Gas Separation of Carbon Dioxide from Methane by Zeolitic Imidazolate Frameworks (ZIFs)

UCLA researchers in the Department of Chemistry and Biochemistry have demonstrated the ability of functionalized zeolitic imidazolate frameworks (ZIFs) to be used in gas separation processes, thereby having industrial applications in natural gas purification and landfill gas separation. 

Planar, Nonpolar M-Plane III-Nitride Films Grown on Miscut Substrates

A method for growing planar nonpolar III-nitride films that have atomically smooth surfaces without any macroscopic surface undulations. 

Ultra-thin Metamaterial "Carpet Cloak" Design

Brief description not available

Solid Solution Phosphors for Use in Solid State White Lighting Applications

A new green- and yellow-emitting phosphor material via solid solution that can be used to create a white light emitting diode. 

A Self-Regenerative Hybrid Tissue Structure For 3D Fabrication of Heart Valves, Blood Vessels and Other Constructs

Researchers at UC Irvine have developed a biocompatible and mechanically stable scaffold for engineering tissues that are capable of self-renewal. The hybrid tissue may be used as replacement heart valve leaflets and may also be used for tissue constructs like blood vessels.

High Performance Thin Films From Solution Processible Two-Dimensional Nanoplates

UCLA researchers in the departments of Chemistry and Materials Science have recently developed a novel material for use in flexible, printed electronics.

Microvascular Exchangers for Heat and Mass Transfer

Micro-structured materials or materials with an embedded microvasculature have advanced the fields of heat exchange, chemical analysis, flow chemistry, fuel cells and carbon capture. In the field of heat exchange, micro-structured composites are being developed to enable fluid-based heat transfer. Such composites may be used in aircraft structures and the ability of the composite to regulate its temperature would decrease an aircraft’s lifecycle costs. In the field of carbon capture, carbon dioxide may be pumped through the microvasculature and a solution of monoethanolamine (MEA) would circulate around the microvasculature. The formation of a carbamate with the MEA and CO2 enables carbon capture. Researchers at the University of California, Irvine have designed a novel microvascular exchanger and this microvascular exchanger has a high heat and mass transfer coefficient when compared to other micro-structured materials. .

Mechanical Linear Actuator That is Low Cost and High Performance

Linear motion is an essential mechanical property used in huge variety of applications. There are multiple ways to create linear motion, including screws, cams, pulleys, pneumatic and hydraulic actuation. Overall performance of these linear actuators can be defined in terms of cost, scale, speed, and efficiency. Current actuators are strong in one or two of these performance categories, which limits their use to specific applications.   UC Berkeley researchers have designed a novel linear actuator that is strong across all four performance categories. The clever Berkeley design provides fast and efficient actuation, and its unique structure is scalable for multiple applications. It is especially conducive to applications that have tight space confines, need a large degree of displacement at a high rate, and are cost constrained.

High Performance, Rare Earth-free Supermagnetostrictive Structures and Materials

Magnetostrictive materials convert magnetic fields into mechanical strain and vice versa. They are widely used in sensors, actuators, electrical motors and other technological devices. The materials currently used for these applications are relatively inefficient (e.g. nickel or iron-aluminum alloys) or are very expensive (e.g. Terfenol-D). To address these challenges, researchers at the University of California, Berkeley, have developed a process framework using incipient martensitic transformations to achieve useful magnetostriction in relatively inexpensive materials. Early laboratory models suggest the Berkeley materials have comparable behavior to rare earth-based counterparts, with preliminary data to suggest superior performance than both rare earth-based and rare earth-free materials on the market today.

Zwitterionic Nano-Adhesives for Improved Wet-Adhesion

Scientists have used catecholic zwitterionic molecules to form an atomically smooth thin (< 2 nm) glue layer on various surfaces including mica, silicon wafers, and copper. 

A Novel MR Angiography Technique

UCLA researchers in the Department of Radiology have demonstrated the FDA approved compound ferumoxytol (a.k.a Feraheme) as a safer and more efficient contrast agent in MRI imaging compared to the traditionally used contrast agent gadolinium. This compound is especially suited for use in pediatric patients with kidney failure.

Low-Pressure High-Capacity Storage System for Sustainable Hydrogen Economy

Hydrogen-fueled cell vehicles could gain ground as global researchers develop better processes to produce hydrogen economically from sustainable resources like solar and wind. On an energy-to-weight basis, hydrogen has nearly three times the energy content of gasoline (120 megajoule or MJ, per kilogram or kg, for hydrogen, versus 44 MJ/kg for gasoline). One problem is storing enough hydrogen on-board to achieve a reasonable driving range of 300 to 400 miles. On energy-to-volume basis, hydrogen takes up nearly three times the volume of gasoline (8 MJ/liter for cryogenic liquid hydrogen versus 32 MJ/liter for gasoline). Another problem is related to next-generation solid absorbents like metal hydrides, which typically show weakness in terms of the amount of gas that can be absorbed and delivered. To address these problems, researchers at the University of California, Berkeley, and Lawrence Berkeley National Laboratory, have developed a composite material using nanostructured metal hydrides that is capable of storing three times more hydrogen per volume at room temperature than a comparable cryogenic liquid hydrogen tank. Furthermore, low hydrogen pressures during absorbing and desorbing have been achieved. This represents a significant economic and safety advantage over technologically complex and costly high-pressure (10,000 psi) hydrogen tanks commonly used in mobile hydrogen storage applications today.

Separation of Organic Solutes Using Membrane Vapor Extraction (MVE)

Separation of a dilute aqueous organic solute is often achieved through liquid-liquid extraction.  However, following contact of the liquids, separation of these liquids is problematic because one liquid dissolves slightly in the other and forms a difficult-to-break micro-emulsion.  Membrane distillation is another conventional separation method based on phase equilibrium differences.  However, this method exhibits low flux through the membrane requiring a large membrane surface area.UC Berkeley researchers have developed a system and method to recover solutes economically without water loss.  The researchers have shown that MVE requires nearly zero energy, can achieve highly efficient separation, and can do so with a high flux similar to that in pervaporation. 

Fullerene Derivatives for Highly Productive Polymer Solar Cells

A chemical structure for fullerene derivatives that increases energy absorption in polymer solar cells.

Methods for Improving Limestone Utilization in Concrete

Researchers at UCLA have improved the utilization of limestone in concrete by developing a system for tailoring the processing parameters to achieve pre-defined mechanical properties and designing processing conditions that enhance the reactivity of the limestone additives.

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