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Revolutionizing Micro-Array Technologies: A Microscopy Method and System Incorporating Nanofeatures

UCLA researchers in the Department of Electrical Engineering have developed a novel lensfree incoherent holographic microscope using a plasmonic aperture.

Rapid, Portable And Cost-Effective Yeast Cell Viability And Concentration Analysis Using Lensfree On-Chip Microscopy And Machine Learning

UCLA researchers in the Department of Electrical Engineering have developed a new portable device to rapidly measure yeast cell viability and concentration using a lab-on-chip design.

Mechanical Process For Creating Particles Using Two Plates

UCLA researchers in the Department of Chemistry and Biochemistry & Physics and Astronomy have developed a novel method to lithograph two polished solid surfaces by using a simple mechanical alignment jig with piezoelectric control and a method of pressing them together and solidifying a material.

Low Cost Wireless Spirometer Using Acoustic Modulation

The present invention relates to portable Spirometry system that uses sound to transmit pulmonary airflow information to a receiver.

Microfluidic Component Package

The present invention describes a component package that enables a microfluidic device to be fixed to a Printed Circuit Board (PCB) or other substrate, and embedded within a larger microfluidic system.

Method and System for Ultra High Dynamic Range Nucleic Acid Quantification

Researchers at UC Irvine developed a device and method that combines the high dynamic range and high accuracy of digital PCR (dPCR) with the real-time analysis of quantitative PCR (qPCR) to achieve a ultra-high dynamic range PCR over 10 to 12 orders of magnitude. The present method is accomplished by a highly integrated design that optimally packs, thermocycles, and images as many as 1 million reaction vessels.

Deep Learning Neural Network Classifier Using Non-Volatile Memory Array

Artificial neural networks that can be used to classify pattern and sequence recognition and play a role in machine learning while remaining energy efficient.

Nanowire Building Block

Nanowires have applications as transistors or bioelectronic devices. Current methods to synthesize nanowires lack the ability to precisely control length, sequence, and terminal functionality. Using this invention as a building block, organic nanowires can be made with controlled length, sequence, and terminal functionality. The organic nanowires made with this invention also exhibit zero-resistance and do not degrade with increased length.

Determining Oil Well Connectivity Using Nanoparticles

UCLA researchers in the Department of Chemistry & Biochemistry, Department of Math, and California NanoSystems Institute (CNSI) have designed methods and systems for monitoring and testing underground wells using sampled nanowires.

Soluble Fluorescent DNA Label

Assays or biosensors that utilize electrochemical or fluorescent techniques often employ DNA electrochemical probes. Current probes have drawbacks, as they have either electronic or fluorescent properties, are not readily water-soluble, and are poorly coupled within a DNA strand. This invention is a DNA electrochemical probe that has both electronic and fluorescent properties, is water-soluble, and can readily incorporate into a DNA strand.

Axi-Symmetric Small-Footprint Gyroscope With Interchangeable Whole-Angle And Rate Operation

The invention is a compact, degenerate mode gyroscope capable of achieving high Q-factor in both whole-angle and rate operation modes.

Artificial cornea implant using nanopatterned synthetic polymer

The device is an artificial corneal implant comprised of a single, nanopatterned material. The device is durable, easy to implant, and robust against bacterial infection and other problems associated with other state-of-the-art ocular devices.

Synthesis Technique to Achieve High-Anisotropy FeNi

Researchers at the University of California, Davis have developed an innovative synthesis approach to achieve high anisotropy L1 FeNi by combining physical vapor deposition and a high speed rapid thermal annealing (RTA).

Building blocks for 3D, modular microfluidics

Researchers at the University of CA, Irvine have developed modular microfluidic platforms consisting of microfluidic building blocks that can be connected in various configurations to construct complete microfluidic devices for different applications.

A Micro/Nanobubble Oxygenated Solutions for Wound Healing and Tissue Preservation

Soft-tissue injuries and organ transplantation are common in modern combat scenarios. Organs and tissues harvested for transplantation need to be preserved during transport, which can be very difficult. Micro and nanobubbles (MNBs) offer a new technology that could supply oxygenation to such tissues prior to transplantation, thus affording better recovery and survival of patients. Described here is a novel device capable of producing MNB solutions that can be used to preserve viability and function of such organs/tissue. Additionally, these solutions may be used with negative pressure wound therapy to heal soft-tissue wounds.

Enhanced Cycle Lifetime With Gel Electrolyte For Mn02 Nanowire Capacitors

The invention is novel way of preparing electrodes for nanowire-based batteries and capacitors with extremely long cycle lifetimes. The proposed assemblies last much longer than any comparable state of the art nanowire energy storage device, without loss of performance, and are comparable to liquid electrolyte-based technologies in terms of their figures of merit.

Finite-State Machines For DNA Information Storage

DNA can store petabytes of information per gram and can last intact for tens of thousands of years.  This makes it an appealing prospect for long-term archival storage.  However, DNA synthesis, sequencing, and replication are prone to errors, which limit its potential as a storage medium.  These errors can be controlled by applying the tools of information theory, treating DNA storage as a noisy channel coding problem.  Several coding schemes for DNA storage have been proposed that address the interrelated issues of error avoidance, error correction and redundancy.  There are currently no schemes that address all the above.    Researchers at UC Berkeley have combine some of these ideas, and introduced new ones, using a modular strategy for code design.  With this method, codes can be assembled to meet requirements including error-avoidance, error-correction (resistant to corruption of the information by substitutions, insertions, duplications, or deletions that are introduced during sequencing or replication of the DNA), and demarcation of metadata.  The DNA generated by the codes is free of short local repeats and other (foldback) structure.  The codes generated by this method are flexible in that they arise by systematic combination of state machines, each machine formally representing a particular transformation of the input sequence.  So, for example, one state machine might be used to introduce a "watermark" signal that helps protect against insertion/deletion errors; another state machine could be used to convert the binary sequence into a ternary sequence (or mixed-radix sequence); another state machine would convert the ternary or mixed-radix sequence into a non-repeating DNA sequence; and another state machine to model the errors that are introduced during sequencing. 

Pyrite Shrink-Wrap Laminate As A Hydroxyl Radical Generator

The invention is a diagnostic technology, as well as a research and development tool. It is a simple, easy to operate, and effective platform for the analysis of pharmaceuticals and biological species. Specifically, this platform generates hydroxyl radicals for oxidative footprinting – a technique commonly employed in protein mapping and analysis. The platform itself is inexpenisve to fabricate, scalable, and requires nothing more than an ordinary pipet to use. In addition, it is highly amenable to scale-up, multiplexing, and automation, and so it holds promise as a high-throughput method for mapping protein structure in support of product development, validation, and regulatory approval in the protein-based therapeutics industry.

Monoclonal Antibody Against Cer164 (Clone 11)

Mouse monoclonal antibody against the human centrosomal protein 164kDa (Cep164). This antibody binds to the phosphorylation site of Cep164 and has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Monoclonal Antibody Against ATR-IP (Clone 5)

Mouse monoclonal antibody against the human ATR-interacting protein (ATR-IP). This antibody has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Monoclonal Antibody Against Cer164 (Clone 26)

Mouse monoclonal antibody against the human centrosomal protein 164kDa (Cep164). This antibody binds to the phosphorylation site of Cep164 and has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Monoclonal Antibody Against PNPase (Clone 4C11)

Mouse monoclonal antibody against the human mitochondrial polyribonucleotide nucleotidyltransferase 1 (PNPase). This antibody has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Monoclonal Antibody Against Pnpase (Clone 2A2)

Mouse monoclonal antibody against the human mitochondrial polyribonucleotide nucleotidyltransferase 1 (PNPase). This antibody has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Monoclonal Antibodies Against Spc24/25 (Clone 2A10)

Mouse hybridoma cell line secret antibody against the human Kinetochore protein Spc24 (SPC24) and Kinetochore protein Spc25 (SPC25). This antibody has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

Monoclonal Antibodies Against Spc24/25 (Clone 2C8)

Mouse hybridoma cell line secret antibody against the human Kinetochore protein Spc24 (SPC24) and Kinetochore protein Spc25 (SPC25). This antibody has been tested for use in immunocytochemistry/immunofluorescence, immunoprecipitation, and western blot.

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