Browse Category:


[Search within category]

A New Methodology For 3D Nanoprinting

Researchers at the University of California, Davis have discovered a novel protocol to enable 3D printing with nanometer precision in all three dimensions using polyelectrolyte (PE) inks and atomic force microscopy.

Manufacturing of Tungsten Scandate Nano-Composite Powder via Sol-Gel Method for High Current Density and Long-Life Cathodes

The researchers at University of California, Davis have developed a new process for manufacturing tungsten scandate nano-composite powder that produces high current density and long-life cathodes for high-power terahertz vacuum electron devices. Scandate tungsten nano-composite cathodes enable advancement of microwave sources that bridge the "Terahertz gap."

Potential Driven Electrochemical Modification of Tissue

Researchers at UC Irvine have developed a minimally invasive technology that uses electrical potentials to perform a variety of to modify and reshape soft tissues such as cartilage

High Performance Thin Films from Solution Processible Two-Dimensional Nanoplates

UCLA researchers in the departments of Chemistry and Materials Science have recently developed a novel material for use in flexible, printed electronics.

Tunable Vapor-Condensed Nano-Lenses

UCLA researchers in the Department of Electrical Engineering have developed an improved and cost-efficient nanolens to visualize nanoparticles and viral particles with 50 fold greater detection and more than 10 fold field-of-view compared to other imaging modalities.

Novel Multivalent Bioassay Reagents

The guiding principle for the creation of biomolecular recognition agents has been that affinity is essential for both strength and specificity.  Monoclonal antibodies, the dominant workhorse of affinity reagents, have mono-valent affinities in the uM-nM range with apparent affinities that can be sub nM with the bi-valency intrinsic in intact immunoglobulin structure.  The avidin-biotin interaction used ubiquitously for biomolecular assembly is femto-molar and both highly specific and essentially irreversible.  High affinity has been proclaimed the essential goal for the selection of useful specific aptamers, though there has been disagreement about a tight coupling of affinity and specificity.  

Self-Latching Piezocomposite Actuator

Brief description not available

Large Area Thermoelectric Module Based on a Non-bulk Semiconductor

Conventional TE module are made of a combination of two types of semiconductors: n-type and p-type. The two types of bulky semiconductor pieces are arranged electrically in series to cover areas specific to different applications. Each semiconductor piece is relatively small because its size is limited by its manufacturing process, therefore a large number of semiconductor pieces are required to cover a large area; and furthermore, both n-type and p-type semiconductors are required because of the way they are assembled in a TE module, which makes it impossible to manufacture a TE module that is practically large and economically inexpensive. An advantage of such conventional TE module is that the open circuit voltage can be increased by connecting a large number of single TE unit in series, but the short circuit current is limited by the cross-section of each semiconductor piece. 

Synthetic Platelets (SynPlats) to Treat Internal & External Bleeding

      Biomaterial nano-particles that mimic the key structural and functional attributes of platelets and have been shown to greatly reduce bleeding time both internally and externally.

Bactericidal Surface Patterns

Brief description not available

Hi-Frequency, Low Power Nanowire Nanoelectrochemical Field-Effect Transistors

Conventional silicon-based transistors face limitations in continued reduced dimensions in order to make electrons move faster. Meanwhile thermodynamics are dictating the amount of power consumed at the off state - by limiting the subthreshold slope of conventional transistors to be at least 60 mV/dec. Motivated by Moore’s Law, the following technology advances the effort to build low power computer logic and memory elements with even more speed.

Real-Time Integrity Monitoring of Reverse Osmosis Membranes

UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a novel method of monitoring the integrity and permeability of reverse osmosis membranes in the presence of nanoparticles and other contaminants.

DNA Double-Write/Double Binding Identity For Micro/Nano Lithography and Self-Assembly Nanofabrication

There have been several attempts to use DNA for photolithographic micro/nanofabrication. For example, exposing immobilized DNA in an un-masked area to ultraviolet light (UV) will cause the DNA to lose the ability to hybridize to complementary DNA sequences, whereas the immobilized DNA in the masked areas will retain the ability to hybridize a complementary sequence. Pattern formation can be achieved by using the difference in DNA assembly in the masked and exposed areas. However, there is an unmet need to improve the usefulness of DNA lithography to fashion more finely defined and complex.

Hydrogen-Treated Semiconductor Metal Oxides For Photoelectrochemical Water Splitting

Titanium dioxide (TiO2) has been extensively investigated as a photoanode for photoelectrochemical (PEC) water splitting, because of its favorable band-edge positions, strong absorption, superior chemical stability, photo-corrosion resistance, and associated low cost; however, reported photocurrent densities and photoconversion efficiencies of TiO2 photoanodes are substantially lower than projected.  UC Santa Cruz researchers have developed a strategy which demonstrates that hydrogen treatment can significantly enhanced the photoconversion efficiency of TiO2 materials by improving their donor density and electrical conductivity.

Silicon Nanostructure Detector With Sub-Bandgap Infrared Response

Silicon nanostructures have attracted enormous attention in the past two decades due to their unique optical properties that cannot be observed in their bulk counterparts. However, since intrinsic silicon has negligible response to infrared photons (λ>1.15 μm) with energies lower than its bandgap energy, it poses a great challenge to use silicon as an active absorbing material for infrared photodetection. In order to realize all-silicon CMOS compatible infrared photodetectors, various approaches have been investigated including incorporation of germanium with silicon as the optically responsive element, two photon absorption process, and surface-plasmon Schottky detectors. The success of these earlier approaches has been limited.

Method Of Forming Flexible Thermoelectric Devices

Thermoelectric devices are made from rigid bulk or bulk like material which are inherently inflexible. Alternative thermoelectric device designs which incorporate semiconducting nanowires are able to be rigid and yet be flexible.   For example, despite the rigidity of semiconducting nanowires they can move independently from each other, enabling flexible thermoelectric device designs. The use of rigid or semi-rigid electrodes for flexible thermoelectric devices causes many difficulties including but not limited to stiffening the device, creating stresses in the active material contacts, and fracturing the active material and contacts. Flexible metallic materials are essential in developing thermoelectric device as envisioned by UCSC researchers.  

Microfluidic-Ribbon Printer

High-throughput, automated, large-scale mircoarry format assay in a short time frame and at low cost.

Method for Synthesis of Nanoparticles in Carbon Nanotube Arrays for the Study of Array Mechanical Properties

A novel approach for modifying and testing the mechanical response of carbon nanotube arrays post-synthesis using metal oxide nanoparticles. 

A Zero-Power, High Throughput Micro, Nanoparticle Printing Via Gravity-Surface Tension Mediated Formation Of Picoliter-Scale Droplets

Current approaches to print micro and nanoparticles are promising, but have serious limitations to commercial applications. These methods require high power consumption and have complicated and costly set-up. These systems are low-throughput, have limited pattern size and resolution-tunability, and difficult alignment. In response to these challenges, investigators at University of California at Berkeley have developed zero-power nanoparticle printing system. This system uses gravity and surface tension to generate and print picoliter-scale droplets for high-throughput, size-tunable printing of micro, nanoparticle assemblies. High-throughput, picoliter-scale droplets are printed by a single step, contact-transferring of the droplets through microporous nanomembrane of a printing head. Rapid evaporative self-assembly of the particles on a hydrophobic surface leads to printing a large array of various microparticles and nanoparticles assemblies of tunable sizes and resolutions. With this technology, continuous printing of single type particles and multiplex printing of various types of particles with accurate alignment are successfully performed. As a demonstration of this innovation, the investigators have produced size-tunable, uniform large arrays of gold nanoparticle assemblies for Surface Enhanced Raman Spectroscopy (SERS) are created. Strong and uniform (<10% variation) SERS signals were obtained and the signal is tunable by controlling the pattern sizes. Also, the superb uniformity of the printed patterns is demonstrated in a quantitative manner. This technology offers a straightforward, efficient methodology to manufacture nanophotonic and nanoelectrical devices in a controllable way with low power and material consumption.

Plasma Induced Nanowrinkles

Leveraging from microfabrication techniques originally developed for the microelectronics industry, researchers have been able to create simple designs such as well-defined and repetitive patterns of grooves, ridges, pits, and waves.Techniques such as photolithography, electron-beam lithography, colloidal lithography, electrospinning, and nanoimprinting are popular methods for fabricating micro and nano topographical features.However, the need for large capital investments and engineering expertise has prevented the widespread use of these fabrication methods in common biological laboratories.Researchers at the University of California, Irvine have developed an ultra-rapid, robust, and inexpensive fabrication method to create multiscaled grooves, ranging from micron to nanometer in size, as biomimetic cell culture substrates.This method only takes a few minutes to perform and does not require any metal deposition.In addition, the size of the nanowrinkles is easily tuned for a multitude of biological applications.

New Light Emission Detection Method Enables High Resolution Optical Imaging of Biological Tissue.

Researchers at the University of California, Irvine have developed a novel method for capturing cellular resolution images of biological tissue at depths of up to several millimeters. Conventional fluorescence detection methods utilize microscope objectives for emission light collection, a less effective approach that is only capable of imaging up to one millimeter deep.To improve upon this standard, the UC researchers minimized light losses by optimizing the system's excitation and detection optics. This new novel method increases the ability to capture cellular resolution images of biological tissues at depths 3x that of previously used methods. The improved method is capable of imaging up to 3 millimeters deep, while previous methods were only capable of depths up to 1 millimeter.

  • Go to Page:

University of California
Innovation Alliances and Services

1111 Franklin Street, 5th Floor,Oakland,CA 94607-5200 |
Tel: 510.587.6000 | Fax: 510.587.6090 |