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Active Nanoplatform with High Drug Loading Capacity for the Diagnosis and Treatment of Cancer

Researchers at the University of California, Davis have developed an active nanoplatform (F/HAPIN) for cancer diagnosis and therapy.

Novel Anti-Bacterial, Anti-Fungal Nanopillared Surface

Medical devices are susceptible to contamination by harmful microbes, such as bacteria and fungi, which form biofilms on device surfaces. These biofilms are often resistant to antibiotics and other current treatments, resulting in over 2 million people per year suffering from diseases related to these contaminating microbes. Death rates for many of these diseases are high, often exceeding 50%. Researchers at UCI have developed a novel anti-bacterial and anti-fungal biocomposite that incorporates a nanopillared surface structure that can be applied as a coating to medical devices.

Peripheral Nerve Repair By Peptide Amphiphile Nanofibers.

UCLA researchers in the Department of Surgery have developed a novel method that promotes directed nerve growth and peripheral nerve regeneration using peptide amphiphile (PA) nanofibers. The combination of conduit and PA nanofiber scaffold offers greater success than currently used methods of bridging with empty conduits. This novel approach may become a substitute for nerve graft for clinical use in the treatment of peripheral nerve injuries.

Biologically Applicable Water-Soluble Heterogeneous Catalysts For Parahydrogen-Induced Polarization

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method of parahydrogen-induced polarization in water using heterogeneous catalysts.

Rapid, Portable And Cost-Effective Yeast Cell Viability And Concentration Analysis Using Lensfree On-Chip Microscopy And Machine Learning

UCLA researchers in the Department of Electrical Engineering have developed a new portable device to rapidly measure yeast cell viability and concentration using a lab-on-chip design.

Process For Recycling Surfactant In Nanoemulsion Production

UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method to separate and recycle surfactants used in the manufacturing of nanoemulsions.

Mechanical Process For Creating Particles Using Two Plates

UCLA researchers in the Department of Chemistry and Biochemistry & Physics and Astronomy have developed a novel method to lithograph two polished solid surfaces by using a simple mechanical alignment jig with piezoelectric control and a method of pressing them together and solidifying a material.

A General Method For Designing Self-Assembling Protein Nanomaterials

UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel computational method for designing proteins that self-assemble to a desired symmetric architecture. This method combines symmetrical docking with interface design, and it can be used to design a wide variety of self-assembling protein nanomaterials. 

Oil-in-Water-in-Oil Multinanoemulsions for Templating Complex Nanoparticles

A process of creating multinanoemulsions using sequential high-energy emulsification.

Tunable Thz Generation In Chip-Scale Graphene

UCLA researchers in the Department of Electrical Engineering have developed a novel tunable and efficient terahertz (THz) plasmon generation on-chip via graphene monolayers.

Determining Oil Well Connectivity Using Nanoparticles

UCLA researchers in the Department of Chemistry & Biochemistry, Department of Math, and California NanoSystems Institute (CNSI) have designed methods and systems for monitoring and testing underground wells using sampled nanowires.

New Method to Increase the Rate of Protein Ligation Catalyzed by the S. Aureus Sortase A Enzyme

UCLA researchers in the Department of Chemistry and Biochemistry have developed a new method to increase the rate of ligation catalyzed by the S. aureus Sortase A enzyme

Fabrication of nano-structures on multiple sides of a non-planar surface

The invention is a breakthrough in the method of fabrication of biomedical devices, making them safer and less infectious. It allows the reproduction of nano-features to one or both side of non-planar biomedical devices. This would improve the cell motility and kill bacteria.

Ultra Light Amphiphilic and Resilient Nanocellulose Aerogels and Foams

Researchers at the University of California, Davis have developed an energy efficient method of producing ultra-light aerogels with excellent dry compressive strength and tunable hydrophobicity by ambient drying of nanocellulose wet gels.

A Micro/Nanobubble Oxygenated Solutions for Wound Healing and Tissue Preservation

Soft-tissue injuries and organ transplantation are common in modern combat scenarios. Organs and tissues harvested for transplantation need to be preserved during transport, which can be very difficult. Micro and nanobubbles (MNBs) offer a new technology that could supply oxygenation to such tissues prior to transplantation, thus affording better recovery and survival of patients. Described here is a novel device capable of producing MNB solutions that can be used to preserve viability and function of such organs/tissue. Additionally, these solutions may be used with negative pressure wound therapy to heal soft-tissue wounds.

Gate-Induced Source Tunneling Field-Effect Transistor (Gistfet)

UCLA researchers in the Department of Electrical Engineering have developed a novel gate-induced source tunneling field-effect transistor (GISTFET).

A New Methodology for 3D Nanoprinting

Researchers at the University of California, Davis have discovered a novel protocol to enable 3D printing with nanometer precision in all three dimensions using polyelectrolyte (PE) inks and atomic force microscopy.

Manufacturing of Tungsten Scandate Nano-Composite Powder via Sol-Gel Method for High Current Density and Long-Life Cathodes

The researchers at University of California, Davis have developed a new process for manufacturing tungsten scandate nano-composite powder that produces high current density and long-life cathodes for high-power terahertz vacuum electron devices. Scandate tungsten nano-composite cathodes enable advancement of microwave sources that bridge the "Terahertz gap."

Potential Driven Electrochemical Modification of Tissue

Researchers at UC Irvine have developed a minimally invasive technology that uses electrical potentials to perform a variety of to modify and reshape soft tissues such as cartilage

High Performance Thin Films from Solution Processible Two-Dimensional Nanoplates

UCLA researchers in the departments of Chemistry and Materials Science have recently developed a novel material for use in flexible, printed electronics.

Tunable Vapor-Condensed Nano-Lenses

UCLA researchers in the Department of Electrical Engineering have developed an improved and cost-efficient nanolens to visualize nanoparticles and viral particles with 50 fold greater detection and more than 10 fold field-of-view compared to other imaging modalities.

Novel Multivalent Bioassay Reagents

The guiding principle for the creation of biomolecular recognition agents has been that affinity is essential for both strength and specificity.  Monoclonal antibodies, the dominant workhorse of affinity reagents, have mono-valent affinities in the uM-nM range with apparent affinities that can be sub nM with the bi-valency intrinsic in intact immunoglobulin structure.  The avidin-biotin interaction used ubiquitously for biomolecular assembly is femto-molar and both highly specific and essentially irreversible.  High affinity has been proclaimed the essential goal for the selection of useful specific aptamers, though there has been disagreement about a tight coupling of affinity and specificity.  

Self-Latching Piezocomposite Actuator

Brief description not available

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