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Methods And Devices for Continuous Analyte Sensing with
Microporous Annealed Particle Gels
UCLA researchers in the Department of Bioengineering have developed novel microporous annealed particle gels for long-term continuous monitoring of blood metabolites.
Bioorthogonal Ligation Mediated Rare-Cell Capture in Microfluidic Devices
Researchers at the UCLA Department of Molecular and Medical Pharmacology have developed a novel NanoVelcro microfluidic chip that is capable of not only effectively enriching circulating tumor cells (CTCs) but also quickly recovering CTCs with well-preserved mRNA and minimal level of white blood cell contamination.
Guided Magnetic Nanospears For Targeted And High-Throughput Intracellular Delivery
UCLA researchers in the Department of Chemistry & Biochemistry and Department of Molecular & Medical Pharmacology have developed novel magnetic nanostructures that can be used to carry and/or deliver biomolecular cargo intracellularly to cells.
Microfluidic Interfacial Magnetic Separation (MIMS)
UCLA researchers in the Department of Medicine and Bioengineering have developed a novel magnetic method for sorting cells.
DNA Nanotechnology for Quick and Sensitive Detection of Nucleic Acids in Point-of-Care (POC) Diagnosis Applications
Researchers led by Dino Di Carlo from the Department of Bioengineering at UCLA have developed a quick, cheap, and accurate method to diagnose viral or bacterial infections.
Label-Free Digital Bright Field Analysis of DNA Amplification
UCLA researchers in the department of Bioengineering have developed a novel method for quantitative analysis of DNA amplification products.
Graphene Nanomesh As A Glucose Sensor
UCLA researchers in the Departments of Chemistry & Biochemistry and of Materials Science & Engineering have developed a glucose sensor based on a graphene nanomesh (GNM) material. The nanoscale GNM glucose sensor provides the potential for in vivo glucose sensing with high selectivity and high sensitivity.
Quantitative Deformability Cytometry: Rapid, Calibrated Measurements Of Cell Mechanical Properties
UCLA researchers in the Department of Integrative Biology and Physiology have developed a novel microfluidic device that enables rapid measurement of cell mechanical properties.
Approach For Efficient Protein Incorporation Into Recombinant Vaults
UCLA researchers in the departments of Medicine, Microbiology, Immunology & Molecular Genetics, and Bioengineering have developed a novel method for loading protein payloads into vault nanoparticle carriers.
Chemiluminescence-Assisted Cell Endocytosis Kinetics Assay
UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a novel method to monitor the intracellular kinetics using the bioluminescent reaction of nanoparticles.
Lensfree Tomographic Imaging
UCLA researchers in the Department of Electrical Engineering have developed a system for lens-free tomographic imaging.
Polyrotaxane Nanoparticles for Delivery of Large Plasmid DNA in Duchenne Muscular Dystrophy
UCLA researchers have designed, synthesized, and validated a polyrotaxane nanocarrier for targeted delivery of large plasmids for gene therapy applications for treatment of Duchenne muscular dystrophy and cancer.
High-Throughput Microfluidic Gene-Editing via Cell Deformability within Microchannels
UCLA researchers in the Departments of Pediatrics and Chemistry & Biochemistry have developed a microfluidic device for delivery of biomolecules into living cells using mechanical deformation, without the fouling issues in current systems.
Plasmonic Nanoparticle Embedded PDMS Micropillar Array and Fabrication Approaches for Large Area Cell Force Sensing
UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed a novel cell force sensor platform with high accuracy over large areas.
Compositions Of Polyion Complex Polypeptide Hydrogels
UCLA researchers in the Department of Bioengineering have developed a new class of cell-compatible copolypeptide hydrogels that possess chain conformation directed polyion complex (PIC) supramolecular architectures.
Mobile Phone Based Fluorescence Multi-Well Plate Reader
UCLA researchers have developed a novel mobile phone-based fluorescence multi-well plate reader.
Computational Sensing Using Low-Cost and Mobile Plasmonic Readers Designed by Machine Learning
UCLA researchers have developed a novel method for computational sensing using low-cost and mobile plasmonic readers designed by machine learning.
Peripheral Nerve Repair By Peptide Amphiphile Nanofibers.
UCLA researchers in the Department of Surgery have developed a novel method that promotes directed nerve growth and peripheral nerve regeneration using peptide amphiphile (PA) nanofibers. The combination of conduit and PA nanofiber scaffold offers greater success than currently used methods of bridging with empty conduits. This novel approach may become a substitute for nerve graft for clinical use in the treatment of peripheral nerve injuries.
Holographic Opto-Fluidic Microscopy
UCLA researchers in the Department of Electrical Engineering have developed a system for holographic opto-fluidic microscopy.
High-Throughput And Label-Free Single Nanoparticle Sizing Based On Time-Resolved On-Chip Microscopy
UCLA researchers in the Department of Electrical Engineering have developed a rapid, low-cost, and label-free methodology for nanoparticle sizing.
Rapid, Portable And Cost-Effective Yeast Cell Viability And Concentration Analysis Using Lensfree On-Chip Microscopy And Machine Learning
UCLA researchers in the Department of Electrical Engineering have developed a new portable device to rapidly measure yeast cell viability and concentration using a lab-on-chip design.
Process For Recycling Surfactant In Nanoemulsion Production
UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel method to separate and recycle surfactants used in the manufacturing of nanoemulsions.
Mechanical Process For Creating Particles Using Two Plates
UCLA researchers in the Department of Chemistry and Biochemistry & Physics and Astronomy have developed a novel method to lithograph two polished solid surfaces by using a simple mechanical alignment jig with piezoelectric control and a method of pressing them together and solidifying a material.
A General Method For Designing Self-Assembling Protein Nanomaterials
UCLA researchers in the Department of Chemistry & Biochemistry have developed a novel computational method for designing proteins that self-assemble to a desired symmetric architecture. This method combines symmetrical docking with interface design, and it can be used to design a wide variety of self-assembling protein nanomaterials.
Drop-Carrier Particles For Digital Assays
UCLA researchers in the Department of Bioengineering have developed a novel drop-carrier particle for single cell or single molecule assays.
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