Platform Strains for Metabolic Engineering of Bioactive Compounds

Tech ID: 21245 / UC Case 2011-034-0

Technology Description

UC San Diego researchers have invented a deletion mutant of a Streptomyces spp. bacterium intended to facilitate the design and creation of new compounds with anti-bacterial, anti-fungal, anti-cancer, or other bioactive properties. These strains have had more of their genetic content deleted than the existing art, providing more utility for metabolic engineering activities and synthetic biology. One would insert plasmids, BACs, etc., that contain genes and pathways encoding for the production of a bioactive compound of interest into this strain. Alternatively, one could integrate these genes and/or pathways directly into the chromosome, if desired.

Patent Status

Patent Pending

Other Information

Categorized As

Related cases

2011-034-0

Keywords

platform strain, novel compound design, anti-bacterial, anti-infective

Contact

University of California, San Diego Technology Transfer Office / invent@ucsd.edu / tel: View Phone Number. Please reference Tech ID #21245.

University of California, San Diego
Technology Transfer Office

9500 Gilman Drive, MC 0910, La Jolla, CA 92093-0910 | invent.ucsd.edu
Tel: 858.534.5815 | Fax: 858.534.7345 | invent@ucsd.edu