New Derivatives of Phosphonate Compounds with Enhanced Anti-viral Activity

Technology Description

A series of novel derivatives of phosphonate compounds has been synthesized. These novel compounds have demonstrated enhanced activity against poxviruses and herpes viruses in tissue culture cells when compared with the unmodified parent molecules. When evaluated against existing alkoxyalkyl analogs of phosphonates, the new compounds are easier and faster to synthesize while retaining the increased bioavailability demonstrated by the alkoxyalkyl phosphonate analogs.

Patent Status