A Chemical Compound with Possible Heterochromatin Remodeling Activity

Tech ID: 18729 / UC Case 2008-109-0

Background

Histone deacetylase inhibitors are currently being evaluated in clinical trials as anti-cancer drugs. They are likely to affect cancer cells because they alter the distribution of heterochromatin with resultant multiple downstream effects that cancer cells cope with only poorly. There is great interest in identifying additional chemical compounds that affect heterochromatin.

Technology Description

Histone deacetylase inhibitors are currently being evaluated in clinical trials as anti-cancer drugs. They are likely to affect cancer cells because they alter the distribution of heterochromatin with resultant multiple downstream effects that cancer cells cope with only poorly. There is great interest in identifying additional chemical compounds that affect heterochromatin.

Applications

Cancer drugs for p53-dependent tumors

Other Information

Categorized As

Related cases

2008-109-0

Contact

Maria Tkachuk / mtkachuk@uci.edu / tel: View Phone Number. Please reference Tech ID #18729.

University of California, Irvine
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