Monoclonal Antibody To Human Dna Polymerase Epsilon Catalytic Subunit

Tech ID: 18601 / UC Case 1999-013-0

Abstract

Human DNA polymerase e contains two apparent subunits of >200 and 55 kDa. Purified polymerase e was used to prepare mouse antiserum capable of recognizing different polymerase e subunits. A mouse monoclonal was identified that had specific recognition for the catalytic subunit of polymerase e (200 kDa).

Reference:
J Biol. Chem. (1995) v270, pp7799-7808.

Applications

Can be used to specifically recognize the catalytic subunit of polymerase e.

Advantages

Does not bind to polymerase a, b, or d.

Other Information

Categorized As

Related cases

1999-013-0

Keywords

research tool, antibody, DNA/RNA synthesis

Contact

Irvin J. Mettler / imettler@berkeley.edu / tel: View Phone Number. Please reference Tech ID #18601.

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