Fully Integrated, Low Cost, Point Of Care Diagnostic System
Tech ID: 17877 / UC Case 2008-015-0
New medical systems are needed to weather the storm of rising healthcare costs. In particular, Point-of-Care (POC) technologies have the potential to keep costs at bay by enabling affordable preventative diagnostics and personal chronic disease monitoring. Many of these POC technologies use detection schemes that rely on the specific marking of target analyte with labels, such as catalytic enzymes, optical markers or magnetic beads. The latter are very useful as labels for bio-assay applications because a) cells exhibit few if any magnetic properties, b) signals from magnetic beads are stable with time, c) magnetic detection functions regardless of the opacity of the sample, and d) magnetic labeling provides added functionality such as magnetic filtration and manipulation. Integrated detection of magnetic beads has been demonstrated using MR spin valves.
Researchers at the University of California have developed a fully integrated system capable of detecting single super-paramagnetic beads using CMOS. The system greatly simplifies detection protocol complexity and reduces overall system cost.
Easy to fabricate, CMOS architecture, Reliable and cost-effective
|Patent Cooperation Treaty||Published Application||WO 2009/091926||09/17/2009||2008-015|
Additional Patent Pending
equipment, detection, point of use, screen, biochip, biochip, screening, detection, diagnostic, diagnostic tool, combinatorial chemistry, healthcare, biochip, research tool