Real-time Characterization of Biological Materials
Tech ID: 11264 / UC Case 2007-081-0
Time and Wavelength Multiplexed Temporal Spectroscopy Apparatus for the Characterization of Biological Materials
Researchers at the University of California, Davis have developed an apparatus that can perform time- and wavelength-resolved spectroscopy capable of recording all data in a "single shot" by wavelength multiplexing and applications of delays to the different spectral components. The device can be used for rapid - near real time spectroscopic characterization of any organic materials (e.g., biological tissues and/or biological systems). Furthermore, when part of a time-resolved laser induced fluorescence system, this device may enable fast diagnosis of tissues and human diseases such as tumors or atherosclerotic plaques.
- Chacterization of biological materials
- Tumor diagnosis
- Atherosclerotic plaque diagnosis
This device is able to read the temporal and spectral information in a "single shot". The entire fluorescence decay function is recorded on a fast detector, and temporal multiplexing of the different spectral bands allows the simultaneous time/wavelength resolution. This is much faster than existing techniques (i.e., time-correlated single photon counting (TCSPC) and spectrometer instruments). In addition, when part of a tissue diagnostic system, this device facilitates fast data acquisition and analysis from biological systems, and thus may allow for near-real time display of diagnostic information.
|United States Of America||Issued Patent||8/089,625||01/03/2012||2007-081|
- Jo, Javier A.
- Marcu, Laura
Fluorescence spectroscopy, fluorescence imaging, biological spectroscopy, time multiplexing, wavelength multiplexing, tumor diagnosis, plaque diagnosis
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