Real-time Characterization of Biological Materials

Tech ID: 11264 / UC Case 2007-081-0

Abstract

Time and Wavelength Multiplexed Temporal Spectroscopy Apparatus for the Characterization of Biological Materials

Full Description

Researchers at the University of California, Davis have developed an apparatus that can perform time- and wavelength-resolved spectroscopy capable of recording all data in a "single shot" by wavelength multiplexing and applications of delays to the different spectral components. The device can be used for rapid - near real time spectroscopic characterization of any organic materials (e.g., biological tissues and/or biological systems). Furthermore, when part of a time-resolved laser induced fluorescence system, this device may enable fast diagnosis of tissues and human diseases such as tumors or atherosclerotic plaques.

Applications

  • Chacterization of biological materials
  • Tumor diagnosis
  • Atherosclerotic plaque diagnosis

Features/Benefits

This device is able to read the temporal and spectral information in a "single shot". The entire fluorescence decay function is recorded on a fast detector, and temporal multiplexing of the different spectral bands allows the simultaneous time/wavelength resolution. This is much faster than existing techniques (i.e., time-correlated single photon counting (TCSPC) and spectrometer instruments). In addition, when part of a tissue diagnostic system, this device facilitates fast data acquisition and analysis from biological systems, and thus may allow for near-real time display of diagnostic information.

Patent Status

Country Type Number Dated Case
United States Of America Issued Patent 8/089,625 01/03/2012 2007-081
 

Inventors

  • Jo, Javier A.
  • Marcu, Laura

Other Information

Categorized As

Related cases

2007-081-0

Keywords

Fluorescence spectroscopy, fluorescence imaging, biological spectroscopy, time multiplexing, wavelength multiplexing, tumor diagnosis, plaque diagnosis

Contact

Nancy E. Rashid / nerashid@ucdavis.edu / tel: View Phone Number. Please reference Tech ID #11264.

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